SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3okx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GYX_A_BEZA1077_0
(HYPOTHETICAL PROTEIN
YDCE)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		4 / 7 CYH A  89
ARG A   8
PRO A  90
SER A 104
 None
 1.50A 1gyxA-3okxA:
undetectable
1gyxB-3okxA:
undetectable		 1gyxA-3okxA:
18.18
1gyxB-3okxA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		5 / 12 ILE A 115
ALA A 116
GLY A  44
GLY A 130
ARG A 103
 None
None
None
None
SAM  A 201 (-4.0A)
 0.88A 2qe6A-3okxA:
undetectable		 2qe6A-3okxA:
23.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		12 / 12 LEU A  37
CYH A  40
HIS A  43
TYR A  76
LEU A  78
ARG A  80
PRO A 105
GLY A 112
THR A 113
SER A 114
CYH A 133
LEU A 134
 SAM  A 201 (-4.5A)
SAM  A 201 (-4.0A)
SAM  A 201 (-4.2A)
None
SAM  A 201 (-4.1A)
None
SAM  A 201 (-3.8A)
SAM  A 201 (-3.6A)
SAM  A 201 (-4.2A)
SAM  A 201 ( 3.9A)
None
SAM  A 201 (-4.2A)
 0.00A 3okxA-3okxA:
27.3		 3okxA-3okxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OKX_A_SAMA201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		4 / 5 SER A  81
ARG A 103
ASP A 132
THR A 137
 SAM  A 201 (-3.1A)
SAM  A 201 (-4.0A)
SAM  A 201 (-3.1A)
SAM  A 201 (-3.2A)
 0.00A 3okxA-3okxA:
27.3		 3okxA-3okxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		3 / 3 LYS A 143
ARG A 146
LYS A 156
 None
 0.02A 3okxA-3okxA:
27.3		 3okxA-3okxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		10 / 12 HIS A  43
TYR A  76
LEU A  78
ARG A  80
PRO A 105
GLY A 112
THR A 113
SER A 114
CYH A 133
LEU A 134
 SAM  A 201 (-4.2A)
None
SAM  A 201 (-4.1A)
None
SAM  A 201 (-3.8A)
SAM  A 201 (-3.6A)
SAM  A 201 (-4.2A)
SAM  A 201 ( 3.9A)
None
SAM  A 201 (-4.2A)
 0.80A 3okxB-3okxA:
23.9		 3okxB-3okxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		11 / 12 LEU A  37
CYH A  40
HIS A  43
TYR A  76
LEU A  78
PRO A 105
GLY A 112
THR A 113
SER A 114
CYH A 133
LEU A 134
 SAM  A 201 (-4.5A)
SAM  A 201 (-4.0A)
SAM  A 201 (-4.2A)
None
SAM  A 201 (-4.1A)
SAM  A 201 (-3.8A)
SAM  A 201 (-3.6A)
SAM  A 201 (-4.2A)
SAM  A 201 ( 3.9A)
None
SAM  A 201 (-4.2A)
 0.16A 3okxB-3okxA:
23.9		 3okxB-3okxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OKX_B_SAMB201_2
(YAEB-LIKE PROTEIN
RPA0152)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		4 / 5 SER A  81
ARG A 103
ASP A 132
THR A 137
 SAM  A 201 (-3.1A)
SAM  A 201 (-4.0A)
SAM  A 201 (-3.1A)
SAM  A 201 (-3.2A)
 0.07A 3okxB-3okxA:
23.9		 3okxB-3okxA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		4 / 8 LEU A 139
VAL A  55
VAL A 118
ILE A  66
 None
 0.99A 4l4cB-3okxA:
undetectable		 4l4cB-3okxA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		4 / 6 ASP A  68
ASN A 125
ALA A 124
ASP A  67
 None
 1.17A 4mdbA-3okxA:
undetectable		 4mdbA-3okxA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3okx YAEB-LIKE PROTEIN
RPA0152
(Rhodopseudomonas
palustris) 		4 / 6 VAL A 140
LEU A  37
ARG A  82
PRO A 105
 None
SAM  A 201 (-4.5A)
None
SAM  A 201 (-3.8A)
 1.08A 6brdB-3okxA:
undetectable		 6brdB-3okxA:
19.87