SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oky'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 5 LYS A 138
LEU A 140
GLU A 150
LEU A 126
 None
 1.17A 1eta1-3okyA:
undetectable		 1eta1-3okyA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 5 LYS A 138
LEU A 140
GLU A 150
ALA A 128
 None
 1.12A 1eta2-3okyA:
1.8		 1eta2-3okyA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 5 LYS A 138
LEU A 140
GLU A 150
LEU A 126
 None
 1.16A 1eta2-3okyA:
1.8		 1eta2-3okyA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 6 LYS A 138
LEU A 140
GLU A 150
LEU A 126
 None
 1.17A 1etb1-3okyA:
undetectable		 1etb1-3okyA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 6 LYS A 138
LEU A 140
GLU A 150
LEU A 126
 None
 1.19A 1etb2-3okyA:
undetectable		 1etb2-3okyA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 ILE A 172
GLU A 123
LEU A 139
ARG A 174
ASP A 179
 GOL  A2006 (-3.9A)
None
None
GOL  A2006 (-4.1A)
None
 1.42A 1p5zB-3okyA:
undetectable		 1p5zB-3okyA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 LEU A 198
GLY A 246
GLY A 170
TYR A 243
LEU A 383
 None
 1.14A 1p91A-3okyA:
undetectable		 1p91A-3okyA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 6 LYS A 138
LEU A 140
GLU A 150
LEU A 126
 None
 1.07A 1sn5A-3okyA:
undetectable		 1sn5A-3okyA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 VAL A 188
ILE A 226
TYR A 243
TYR A 215
SER A 199
 None
 1.39A 2iyfB-3okyA:
undetectable		 2iyfB-3okyA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_A_ETVA302_1
(DEOXYCYTIDINE KINASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 ILE A 172
GLU A 123
LEU A 139
ARG A 174
ASP A 179
 GOL  A2006 (-3.9A)
None
None
GOL  A2006 (-4.1A)
None
 1.37A 2no6A-3okyA:
undetectable		 2no6A-3okyA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_B_ETVB302_1
(DEOXYCYTIDINE KINASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 ILE A 172
GLU A 123
LEU A 139
ARG A 174
ASP A 179
 GOL  A2006 (-3.9A)
None
None
GOL  A2006 (-4.1A)
None
 1.39A 2no6B-3okyA:
0.0		 2no6B-3okyA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 ILE A 172
GLU A 123
LEU A 139
ARG A 174
ASP A 179
 GOL  A2006 (-3.9A)
None
None
GOL  A2006 (-4.1A)
None
 1.37A 2noaB-3okyA:
undetectable		 2noaB-3okyA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 7 GLY A 185
THR A 197
MET A 168
SER A 160
 None
 1.25A 2o5yH-3okyA:
5.3
2o5yL-3okyA:
5.1		 2o5yH-3okyA:
15.96
2o5yL-3okyA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 TYR A 276
GLN A 343
GLN A 311
HIS A 347
PRO A 349
 None
 1.20A 2owwA-3okyA:
undetectable		 2owwA-3okyA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 LEU A 578
PRO A 616
THR A 600
GLY A 597
LEU A 580
 None
 1.22A 2uvnA-3okyA:
undetectable		 2uvnA-3okyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 ILE A 280
VAL A 419
GLU A 261
THR A 262
ILE A 241
 None
 1.14A 2vn0A-3okyA:
undetectable		 2vn0A-3okyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 8 LEU A 322
SER A 444
ARG A 459
VAL A 446
 None
 0.93A 3ax9A-3okyA:
undetectable		 3ax9A-3okyA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 7 ASP A 120
SER A 122
SER A 175
ASP A 286
 GOL  A2006 (-4.2A)
GOL  A2006 (-3.0A)
None
None
 1.22A 3bc9A-3okyA:
5.4		 3bc9A-3okyA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 5 TYR A 293
ILE A 241
TYR A 243
THR A 167
 None
 1.24A 3dgqA-3okyA:
undetectable		 3dgqA-3okyA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 7 LYS A 154
GLU A 156
ASP A 214
SER A 223
 None
 1.40A 3dzgA-3okyA:
undetectable		 3dzgA-3okyA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 8 SER A 489
LEU A 493
TYR A 496
TYR A 494
 None
 0.91A 3i45A-3okyA:
undetectable		 3i45A-3okyA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 LEU A  53
TYR A 245
ALA A 436
LEU A 495
ALA A 316
 None
 1.29A 3ou7C-3okyA:
undetectable		 3ou7C-3okyA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 8 LEU A 424
ALA A 460
SER A 444
SER A 437
 None
 0.90A 3rodA-3okyA:
undetectable		 3rodA-3okyA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 7 SER A 434
VAL A 475
ILE A 482
TYR A 438
 None
 1.07A 3tneB-3okyA:
undetectable		 3tneB-3okyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 3oky PLEXIN-A2
(Mus
musculus) 		3 / 3 LYS A 138
LEU A 140
ALA A 128
 None
 0.64A 4iizA-3okyA:
undetectable		 4iizA-3okyA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 8 LYS A 138
LEU A 140
GLU A 150
ALA A 128
 None
 0.76A 4ik6B-3okyA:
undetectable		 4ik6B-3okyA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 7 LEU A 159
VAL A 136
PRO A 151
TYR A 215
 None
 0.77A 4lb2A-3okyA:
undetectable		 4lb2A-3okyA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 7 LEU A 159
VAL A 136
PRO A 151
TYR A 215
 None
 1.05A 4lb2A-3okyA:
undetectable		 4lb2A-3okyA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 VAL A 188
ILE A 226
TYR A 243
TYR A 215
SER A 199
 None
 1.37A 4m83B-3okyA:
undetectable		 4m83B-3okyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 ALA A 357
GLY A 466
GLY A 467
ALA A 460
SER A 444
 None
 0.92A 4qvlK-3okyA:
undetectable
4qvlL-3okyA:
undetectable		 4qvlK-3okyA:
14.71
4qvlL-3okyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 ALA A 357
GLY A 466
GLY A 467
ALA A 460
SER A 444
 None
 0.92A 4qvlY-3okyA:
undetectable
4qvlZ-3okyA:
undetectable		 4qvlY-3okyA:
14.71
4qvlZ-3okyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 10 ALA A 357
GLY A 466
GLY A 467
ALA A 460
SER A 444
 None
 0.91A 4qvmY-3okyA:
undetectable
4qvmZ-3okyA:
undetectable		 4qvmY-3okyA:
14.86
4qvmZ-3okyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 ALA A 357
GLY A 466
GLY A 467
ALA A 460
SER A 444
 None
 0.95A 4qw1K-3okyA:
undetectable
4qw1L-3okyA:
undetectable		 4qw1K-3okyA:
14.71
4qw1L-3okyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 7 ILE A 184
LEU A 213
LEU A 127
ILE A 172
 None
None
None
GOL  A2006 (-3.9A)
 0.86A 4rmjA-3okyA:
undetectable		 4rmjA-3okyA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 LEU A 483
SER A 499
LEU A 117
GLY A  65
ALA A  66
 None
 1.01A 4rrwC-3okyA:
undetectable		 4rrwC-3okyA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 LEU A 483
SER A 499
LEU A 117
GLY A  65
ALA A  66
 None
 1.01A 4rrzC-3okyA:
undetectable		 4rrzC-3okyA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 5 GLY A  86
THR A  85
GLY A 130
GLU A  88
 None
 1.16A 4v20A-3okyA:
undetectable		 4v20A-3okyA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3oky PLEXIN-A2
(Mus
musculus) 		3 / 3 THR A 600
HIS A 565
LEU A 580
 None
 0.73A 5axdA-3okyA:
undetectable		 5axdA-3okyA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 ALA A 357
GLY A 466
GLY A 467
ALA A 460
SER A 444
 None
 0.93A 5bxnK-3okyA:
undetectable
5bxnL-3okyA:
undetectable		 5bxnK-3okyA:
14.71
5bxnL-3okyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 11 ALA A 357
GLY A 466
GLY A 467
ALA A 460
SER A 444
 None
 0.93A 5bxnY-3okyA:
undetectable
5bxnZ-3okyA:
undetectable		 5bxnY-3okyA:
14.71
5bxnZ-3okyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 10 GLY A 135
LEU A 159
LEU A 213
ARG A 201
GLU A 156
 None
 1.37A 5hwkA-3okyA:
undetectable		 5hwkA-3okyA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 10 GLY A 135
LEU A 159
LEU A 213
ARG A 201
GLU A 156
 None
 1.36A 5hwkB-3okyA:
undetectable		 5hwkB-3okyA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3oky PLEXIN-A2
(Mus
musculus) 		5 / 12 ILE A 241
PHE A 239
LEU A 235
THR A 277
PRO A 260
 None
 1.10A 5xxiA-3okyA:
undetectable		 5xxiA-3okyA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3oky PLEXIN-A2
(Mus
musculus) 		4 / 7 HIS A  56
THR A  59
ARG A 141
ASP A 143
 None
 1.28A 6mn4E-3okyA:
undetectable		 6mn4E-3okyA:
19.14