SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3okz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		4 / 8 GLN A 226
LEU A  63
LEU A 125
SER A  82
 None
 1.10A 1hk2A-3okzA:
undetectable		 1hk2A-3okzA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		5 / 6 MET A  99
VAL A  88
ILE A 230
ILE A  62
LEU A  63
 None
 1.28A 3hegA-3okzA:
undetectable		 3hegA-3okzA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		5 / 12 ALA A 130
GLY A 132
GLY A  80
SER A  79
ASP A  68
 None
 1.22A 3ou7A-3okzA:
undetectable		 3ou7A-3okzA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		5 / 12 ALA A 130
GLY A 132
GLY A  80
SER A  79
ASP A  68
 None
 1.24A 3ou7D-3okzA:
undetectable		 3ou7D-3okzA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUM_A_CCSA375_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		4 / 4 GLN A 223
SER A 101
GLY A 221
LYS A 224
 None
 1.40A 3rumA-3okzA:
0.0		 3rumA-3okzA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		5 / 10 LEU A  87
LEU A 102
LEU A 125
LYS A 315
ILE A 314
 None
 1.32A 4mk4A-3okzA:
undetectable		 4mk4A-3okzA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		3 / 3 ARG A 222
GLU A 186
ARG A 104
 None
 1.00A 4mwvA-3okzA:
undetectable		 4mwvA-3okzA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		4 / 7 THR A 100
LEU A  87
THR A  98
LEU A 318
 None
 0.91A 4z91F-3okzA:
undetectable
4z91G-3okzA:
undetectable
4z91H-3okzA:
undetectable
4z91I-3okzA:
undetectable
4z91J-3okzA:
undetectable		 4z91F-3okzA:
20.82
4z91G-3okzA:
20.82
4z91H-3okzA:
20.82
4z91I-3okzA:
20.82
4z91J-3okzA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		4 / 6 ARG A 225
ASP A 219
GLY A 218
ASP A 215
 None
 1.11A 5hp1A-3okzA:
1.0		 5hp1A-3okzA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		4 / 7 SER A 209
LEU A 206
MET A 157
LEU A 160
 None
 0.96A 5u4sA-3okzA:
undetectable		 5u4sA-3okzA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3okz PUTATIVE
UNCHARACTERIZED
PROTEIN GBS0355
(Streptococcus
agalactiae) 		4 / 8 SER A 209
LEU A 206
MET A 157
LEU A 160
 None
 0.98A 5u4sB-3okzA:
undetectable		 5u4sB-3okzA:
23.01