SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3olm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 SER A 774
VAL A 781
LEU A 733
PRO A 772
 None
 0.81A 1fduB-3olmA:
undetectable		 1fduB-3olmA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_A_CHCA202_1
(BILE ACID RECEPTOR)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 468
PHE A 504
SER A 508
PHE A 512
ILE A 548
 None
 1.50A 1osvA-3olmA:
0.0		 1osvA-3olmA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.93A 1rxcB-3olmA:
undetectable		 1rxcB-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 1.04A 1rxcC-3olmA:
undetectable		 1rxcC-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.99A 1rxcD-3olmA:
undetectable		 1rxcD-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.90A 1rxcE-3olmA:
undetectable		 1rxcE-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.91A 1rxcF-3olmA:
undetectable		 1rxcF-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.92A 1rxcI-3olmA:
undetectable		 1rxcI-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.95A 1rxcK-3olmA:
undetectable		 1rxcK-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.92A 1rxcL-3olmA:
undetectable		 1rxcL-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 483
GLY A 756
PRO A 757
 None
 0.70A 2hreD-3olmA:
undetectable		 2hreD-3olmA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 507
ILE A 457
VAL A 459
ALA A 468
 None
 0.91A 2j5mA-3olmA:
undetectable		 2j5mA-3olmA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 THR A 410
ARG A 436
ILE A 440
ASP A 407
 None
 1.06A 2xytE-3olmA:
undetectable		 2xytE-3olmA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 THR A 410
ARG A 436
ILE A 440
ASP A 407
 None
 1.05A 2xytH-3olmA:
undetectable		 2xytH-3olmA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 464
PHE A 488
ARG A 560
THR A 740
 None
 1.04A 3ag2N-3olmA:
undetectable
3ag2W-3olmA:
undetectable		 3ag2N-3olmA:
20.60
3ag2W-3olmA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.93A 3kvvA-3olmA:
undetectable		 3kvvA-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.97A 3kvvB-3olmA:
undetectable		 3kvvB-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.96A 3kvvC-3olmA:
undetectable		 3kvvC-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.99A 3kvvD-3olmA:
undetectable		 3kvvD-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.94A 3kvvE-3olmA:
undetectable		 3kvvE-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.95A 3kvvF-3olmA:
undetectable		 3kvvF-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 512
PHE A 504
LEU A 507
GLY A 666
PHE A 667
 None
 1.23A 3tbgA-3olmA:
undetectable		 3tbgA-3olmA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 512
PHE A 504
LEU A 507
GLY A 666
PHE A 667
 None
 1.26A 3tbgC-3olmA:
undetectable		 3tbgC-3olmA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA503_0
(OXIDOREDUCTASE,
FMN-BINDING)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 SER A 444
TYR A 441
PHE A 442
PHE A 679
 None
 1.48A 4awuA-3olmA:
0.0		 4awuA-3olmA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.97A 4e1vA-3olmA:
undetectable		 4e1vA-3olmA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.93A 4e1vB-3olmA:
undetectable		 4e1vB-3olmA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.95A 4e1vC-3olmA:
undetectable		 4e1vC-3olmA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.92A 4e1vD-3olmA:
undetectable		 4e1vD-3olmA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.97A 4e1vE-3olmA:
undetectable		 4e1vE-3olmA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.93A 4e1vF-3olmA:
undetectable		 4e1vF-3olmA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.89A 4e1vG-3olmA:
undetectable		 4e1vG-3olmA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 553
MET A 664
ILE A 688
VAL A 556
 None
 0.91A 4e1vH-3olmA:
undetectable		 4e1vH-3olmA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 464
PHE A 488
ARG A 560
THR A 740
 None
 0.94A 5b1aN-3olmA:
undetectable
5b1aW-3olmA:
undetectable		 5b1aN-3olmA:
20.60
5b1aW-3olmA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 468
LEU A 507
GLY A 555
LEU A 480
ILE A 457
 None
 1.07A 5m24A-3olmA:
undetectable		 5m24A-3olmA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 464
PHE A 488
ARG A 560
THR A 740
 None
 1.16A 5z84N-3olmA:
undetectable
5z84W-3olmA:
undetectable		 5z84N-3olmA:
20.60
5z84W-3olmA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 465
TYR A 469
ALA A 662
ILE A 537
LEU A 518
 None
 1.23A 6aybA-3olmA:
undetectable		 6aybA-3olmA:
21.58