SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3om3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		3 / 3 GLU B 189
TYR B 185
PHE B 249
 None
 0.95A 1eqbB-3om3B:
undetectable		 1eqbB-3om3B:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		3 / 3 GLU B 189
TYR B 185
PHE B 249
 None
 0.95A 1eqbA-3om3B:
undetectable		 1eqbA-3om3B:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		3 / 3 GLU B 189
TYR B 185
PHE B 249
 None
 0.95A 1eqbD-3om3B:
undetectable		 1eqbD-3om3B:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		3 / 3 GLU B 189
TYR B 185
PHE B 249
 None
 0.96A 1eqbC-3om3B:
undetectable		 1eqbC-3om3B:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1598_0
(NITROUS OXIDE
REDUCTASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		4 / 4 HIS B 217
CYH B 252
CYH B 256
MET B 263
 CU1  B 288 (-3.2A)
CU1  B 288 ( 2.2A)
CU1  B 287 ( 2.3A)
CU1  B 288 (-2.3A)
 0.47A 2iwkA-3om3B:
9.4		 2iwkA-3om3B:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		3 / 3 CYH B 252
CYH B 256
HIS B 260
 CU1  B 288 ( 2.2A)
CU1  B 287 ( 2.3A)
CU1  B 287 (-3.0A)
 0.25A 2iwkA-3om3B:
9.4		 2iwkA-3om3B:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1598_0
(NITROUS OXIDE
REDUCTASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		4 / 4 HIS B 217
CYH B 252
CYH B 256
MET B 263
 CU1  B 288 (-3.2A)
CU1  B 288 ( 2.2A)
CU1  B 287 ( 2.3A)
CU1  B 288 (-2.3A)
 0.47A 2iwkB-3om3B:
9.5		 2iwkB-3om3B:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		3 / 3 CYH B 252
CYH B 256
HIS B 260
 CU1  B 288 ( 2.2A)
CU1  B 287 ( 2.3A)
CU1  B 287 (-3.0A)
 0.24A 2iwkB-3om3B:
9.5		 2iwkB-3om3B:
17.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_B_CUB1004_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		4 / 4 HIS B 217
CYH B 252
CYH B 256
MET B 263
 CU1  B 288 (-3.2A)
CU1  B 288 ( 2.2A)
CU1  B 287 ( 2.3A)
CU1  B 288 (-2.3A)
 0.08A 3dtuB-3om3B:
35.5		 3dtuB-3om3B:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		3 / 3 CYH B 252
CYH B 256
HIS B 260
 CU1  B 288 ( 2.2A)
CU1  B 287 ( 2.3A)
CU1  B 287 (-3.0A)
 0.09A 3dtuB-3om3B:
35.5		 3dtuB-3om3B:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		3 / 3 CYH B 252
CYH B 256
HIS B 260
 CU1  B 288 ( 2.2A)
CU1  B 287 ( 2.3A)
CU1  B 287 (-3.0A)
 0.08A 3dtuD-3om3B:
36.2		 3dtuD-3om3B:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DTU_D_CUD4_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		4 / 4 HIS B 217
CYH B 252
CYH B 256
MET B 263
 CU1  B 288 (-3.2A)
CU1  B 288 ( 2.2A)
CU1  B 287 ( 2.3A)
CU1  B 288 (-2.3A)
 0.10A 3dtuD-3om3B:
36.2		 3dtuD-3om3B:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 3om3 CYTOCHROME C OXIDASE
SUBUNIT 2
(Rhodobacter
sphaeroides) 		5 / 12 PRO B 232
GLY B 233
VAL B 138
VAL B 226
LEU B 238
 None
 1.06A 3m6wA-3om3B:
undetectable		 3m6wA-3om3B:
19.53