SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3omb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 7 PHE A 238
GLY A 241
ILE A 461
TYR A 460
 None
 0.64A 11gsB-3ombA:
undetectable		 11gsB-3ombA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 9 VAL A 422
VAL A  43
ILE A 355
ALA A 369
LEU A 372
 None
 1.12A 1eqgA-3ombA:
undetectable		 1eqgA-3ombA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 VAL A 422
VAL A  43
ILE A 355
ALA A 369
LEU A 372
 None
 1.14A 1eqgB-3ombA:
undetectable		 1eqgB-3ombA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 6 LEU A 167
THR A 221
TYR A 223
TYR A 447
 None
 1.49A 1qvuA-3ombA:
1.2		 1qvuA-3ombA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 6 LEU A 372
MET A  54
LEU A 417
ILE A 425
 None
 1.02A 1z95A-3ombA:
undetectable		 1z95A-3ombA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 11 ASN A 211
ILE A 296
TYR A 323
ALA A 302
ASP A 287
 None
 1.42A 2iyfA-3ombA:
undetectable		 2iyfA-3ombA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 6 THR A 221
GLU A 244
MET A 490
PHE A 486
 None
 1.42A 2w98B-3ombA:
undetectable		 2w98B-3ombA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 6 LEU A 417
VAL A 422
VAL A  43
VAL A  97
 None
 0.96A 2z97A-3ombA:
undetectable		 2z97A-3ombA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 7 ASN A  98
ALA A 365
ALA A 369
ILE A  94
 None
 0.76A 3a2qA-3ombA:
undetectable		 3a2qA-3ombA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		3 / 3 ASP A 153
LEU A 421
GLN A  51
 None
 0.81A 3g4lA-3ombA:
undetectable		 3g4lA-3ombA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 4 LEU A 215
MET A 210
ILE A 234
ASP A 342
 None
 1.12A 3hecA-3ombA:
undetectable		 3hecA-3ombA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 8 TYR A 159
GLU A 439
PHE A 382
ILE A 390
 None
 0.99A 3jz0B-3ombA:
undetectable		 3jz0B-3ombA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 8 SER A 521
ASN A 482
GLU A 484
ILE A 485
 None
 0.96A 4d33A-3ombA:
undetectable		 4d33A-3ombA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 7 SER A 521
ASN A 482
GLU A 484
ILE A 485
 None
 0.97A 4d33B-3ombA:
undetectable		 4d33B-3ombA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 8 SER A 521
ASN A 482
GLU A 484
ILE A 485
 None
 0.97A 4d39A-3ombA:
undetectable		 4d39A-3ombA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 7 SER A 521
ASN A 482
GLU A 484
ILE A 485
 None
 0.98A 4d39B-3ombA:
undetectable		 4d39B-3ombA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		6 / 12 LEU A 421
LEU A 417
GLY A 416
GLN A  51
ILE A 390
VAL A 400
 None
 1.37A 4ok1A-3ombA:
undetectable		 4ok1A-3ombA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 LEU A 421
LEU A 417
GLY A 416
GLN A  51
ILE A 390
 None
 1.26A 4oktA-3ombA:
undetectable		 4oktA-3ombA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 LEU A 417
GLY A 416
GLN A  51
ILE A 390
VAL A 400
 None
 1.23A 4okwA-3ombA:
undetectable		 4okwA-3ombA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WMZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 9 PHE A 486
ILE A 485
PHE A 220
GLY A 246
MET A 226
 None
 1.02A 4wmzA-3ombA:
0.3		 4wmzA-3ombA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 7 THR A 259
LEU A 258
LEU A 513
THR A 522
 None
 0.88A 4z90A-3ombA:
2.5
4z90B-3ombA:
undetectable
4z90C-3ombA:
undetectable
4z90D-3ombA:
undetectable
4z90E-3ombA:
undetectable		 4z90A-3ombA:
21.05
4z90B-3ombA:
21.05
4z90C-3ombA:
21.05
4z90D-3ombA:
21.05
4z90E-3ombA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 PHE A 486
ILE A 485
PHE A 220
GLY A 246
MET A 226
 None
 1.08A 4zdyA-3ombA:
undetectable		 4zdyA-3ombA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 7 PHE A 486
ILE A 485
PHE A 220
GLY A 246
MET A 226
 None
 1.12A 4zdzA-3ombA:
3.1		 4zdzA-3ombA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 7 PHE A 486
ILE A 485
PHE A 220
GLY A 246
 None
 0.87A 4ze3A-3ombA:
undetectable		 4ze3A-3ombA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 8 PHE A 486
ILE A 485
PHE A 220
GLY A 246
 None
 0.89A 5esfA-3ombA:
undetectable		 5esfA-3ombA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 8 PHE A 486
ILE A 485
PHE A 220
GLY A 246
 None
 0.90A 5esjA-3ombA:
undetectable		 5esjA-3ombA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		4 / 7 PHE A 486
ILE A 485
PHE A 220
GLY A 246
 None
 0.92A 5esmA-3ombA:
undetectable		 5esmA-3ombA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1
(Bifidobacterium
longum) 		5 / 12 SER A 256
THR A 489
GLY A 246
VAL A 242
PHE A 220
 None
 1.45A 5jo9A-3ombA:
undetectable		 5jo9A-3ombA:
19.81