SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oms'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 3oms PHNB PROTEIN
(Bacillus
cereus) 		5 / 12 ALA A  18
GLY A  16
ILE A  66
SER A  68
ALA A  54
 None
 1.01A 1ve3A-3omsA:
undetectable		 1ve3A-3omsA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3oms PHNB PROTEIN
(Bacillus
cereus) 		5 / 12 ALA A  18
GLY A  16
ILE A  66
SER A  68
ALA A  54
 None
 0.99A 1ve3B-3omsA:
undetectable		 1ve3B-3omsA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3oms PHNB PROTEIN
(Bacillus
cereus) 		4 / 7 PHE A  14
ALA A  18
THR A  26
LEU A  58
 None
 0.83A 2wx2A-3omsA:
undetectable		 2wx2A-3omsA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3oms PHNB PROTEIN
(Bacillus
cereus) 		4 / 8 PHE A  14
ALA A  18
THR A  26
LEU A  58
 None
 0.72A 2wx2B-3omsA:
undetectable		 2wx2B-3omsA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3oms PHNB PROTEIN
(Bacillus
cereus) 		4 / 6 ILE A  92
ASP A  93
GLY A 110
HIS A  97
 None
None
EDO  A 501 ( 3.9A)
None
 0.83A 4oltA-3omsA:
undetectable		 4oltA-3omsA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 3oms PHNB PROTEIN
(Bacillus
cereus) 		4 / 6 ILE A  92
ASP A  93
GLY A 110
HIS A  97
 None
None
EDO  A 501 ( 3.9A)
None
 0.84A 4oltB-3omsA:
undetectable		 4oltB-3omsA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 3oms PHNB PROTEIN
(Bacillus
cereus) 		5 / 12 PHE A 118
PHE A  14
ALA A  18
THR A  26
LEU A  58
 None
 1.15A 6aycA-3omsA:
undetectable		 6aycA-3omsA:
21.55