SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3omx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3omx CG14216
(Drosophila
melanogaster) 		4 / 8 ARG A  42
ASN A  16
SER A  15
VAL A  43
 None
None
VO4  A 300 (-4.0A)
None
 1.28A 1u1jA-3omxA:
undetectable		 1u1jA-3omxA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3omx CG14216
(Drosophila
melanogaster) 		3 / 3 MET A  85
CYH A  13
PRO A  96
 None
VO4  A 300 (-2.3A)
None
 1.28A 3h52C-3omxA:
undetectable		 3h52C-3omxA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3omx CG14216
(Drosophila
melanogaster) 		4 / 4 LEU A  45
PRO A  46
LEU A  82
ARG A  88
 None
 0.84A 3hcoA-3omxA:
5.0		 3hcoA-3omxA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3omx CG14216
(Drosophila
melanogaster) 		4 / 5 LEU A  45
PRO A  46
LEU A  82
ARG A  88
 None
 0.99A 4klrA-3omxA:
4.5		 4klrA-3omxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3omx CG14216
(Drosophila
melanogaster) 		3 / 3 LEU A  45
PRO A  46
ARG A  88
 None
 0.73A 4klrB-3omxA:
5.2		 4klrB-3omxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3omx CG14216
(Drosophila
melanogaster) 		5 / 9 VAL A 140
GLY A 152
ALA A 153
THR A 157
VAL A 110
 None
 0.99A 4r21B-3omxA:
undetectable		 4r21B-3omxA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3omx CG14216
(Drosophila
melanogaster) 		4 / 6 PHE A 180
LEU A 138
ASN A 139
ARG A 183
 None
 1.45A 4yv5B-3omxA:
undetectable		 4yv5B-3omxA:
17.19