SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3on2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 3on2 PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		6 / 11 GLY A 119
ALA A 120
ASP A  61
VAL A 124
GLY A 113
VAL A 125
 None
 1.31A 1t7jA-3on2A:
undetectable		 1t7jA-3on2A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3on2 PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 GLY A  29
GLU A 106
ASP A  31
 None
 0.59A 2b25B-3on2A:
undetectable		 2b25B-3on2A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3on2 PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 ILE A 167
ALA A 168
ALA A 172
VAL A 181
ARG A 105
 None
 1.04A 2fr3A-3on2A:
undetectable		 2fr3A-3on2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3on2 PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		4 / 6 LEU A  69
PHE A  53
ASP A  55
GLU A  65
 None
 1.10A 2vn1B-3on2A:
undetectable		 2vn1B-3on2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 3on2 PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		6 / 12 GLY A 119
ALA A 120
ASP A  61
VAL A 124
GLY A 113
VAL A 125
 None
 1.27A 3el5B-3on2A:
undetectable		 3el5B-3on2A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3on2 PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 LEU A 107
GLU A  76
GLY A  67
SER A  66
LEU A  71
 None
 1.42A 3ou6D-3on2A:
undetectable		 3ou6D-3on2A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 3on2 PROBABLE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 SER A  12
ARG A  14
HIS A  52
 None
 1.02A 4mjwA-3on2A:
undetectable
4mjwB-3on2A:
undetectable		 4mjwA-3on2A:
18.21
4mjwB-3on2A:
18.21