SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3on5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		3 / 3 CYH A 216
PHE A 220
PHE A 221
 None
 1.02A 3cr5X-3on5A:
undetectable		 3cr5X-3on5A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		3 / 3 GLU A 217
PHE A 220
GLN A 215
 None
 0.87A 3r55A-3on5A:
undetectable		 3r55A-3on5A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		4 / 5 HIS A  24
SER A  97
THR A  73
GLU A  33
 None
 1.38A 3tm4A-3on5A:
4.4		 3tm4A-3on5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		4 / 5 HIS A  24
SER A  97
THR A  73
GLU A  33
 None
 1.38A 3tm4B-3on5A:
4.3		 3tm4B-3on5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		4 / 8 VAL A 247
TYR A 271
ILE A 249
ILE A 185
 None
 0.98A 4afgD-3on5A:
undetectable
4afgE-3on5A:
undetectable		 4afgD-3on5A:
18.68
4afgE-3on5A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		4 / 4 LEU A 195
SER A 313
LEU A 275
LEU A 183
 None
 1.01A 4n09A-3on5A:
5.1		 4n09A-3on5A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		4 / 8 LEU A  58
VAL A  98
ILE A  96
MET A  37
 None
 0.95A 4oj4A-3on5A:
undetectable		 4oj4A-3on5A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA305_0
(THAUMATIN-1)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		4 / 5 LYS A 122
ILE A 142
PHE A 125
VAL A 158
 None
 1.14A 4tvtA-3on5A:
undetectable		 4tvtA-3on5A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		3 / 3 ARG A 242
ASP A 245
TYR A 205
 None
 0.90A 4yo9B-3on5A:
undetectable		 4yo9B-3on5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3on5 BH1974 PROTEIN
(Bacillus
halodurans) 		4 / 4 ARG A 323
SER A   2
ASP A   3
HIS A 175
 None
 1.19A 5zhmA-3on5A:
1.0		 5zhmA-3on5A:
25.96