SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3on6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 TRP A 107
ARG A 109
ASP A 110
TRP A 403
GLU A 439
 EDO  A 492 (-3.3A)
None
EDO  A 492 (-3.0A)
None
None
 0.72A 1agmA-3on6A:
24.3		 1agmA-3on6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 TRP A 107
ARG A 109
ASP A 110
TRP A 403
GLU A 439
 EDO  A 492 (-3.3A)
None
EDO  A 492 (-3.0A)
None
None
 0.72A 1agmA-3on6A:
24.3		 1agmA-3on6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 TRP A 107
ARG A 109
ASP A 110
TRP A 403
GLU A 439
 EDO  A 492 (-3.3A)
None
EDO  A 492 (-3.0A)
None
None
 0.74A 1gahA-3on6A:
23.9		 1gahA-3on6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 ASP A 346
GLY A 391
SER A 440
THR A 450
 None
 0.88A 1m4iA-3on6A:
undetectable		 1m4iA-3on6A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 TYR A 368
THR A 413
VAL A 375
VAL A 349
 None
PEG  A 495 ( 4.8A)
None
None
 1.12A 1uyuA-3on6A:
undetectable		 1uyuA-3on6A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 TRP A 107
ARG A 109
ASP A 110
TRP A 403
GLU A 439
 EDO  A 492 (-3.3A)
None
EDO  A 492 (-3.0A)
None
None
 0.77A 2f6dA-3on6A:
24.7		 2f6dA-3on6A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 LEU A 257
ALA A 281
ILE A 179
SER A 277
 None
 0.99A 2othA-3on6A:
undetectable		 2othA-3on6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 MET A 408
PHE A 412
TYR A 357
PRO A 404
MET A 437
 None
PEG  A 495 (-4.6A)
PEG  A 495 (-4.7A)
None
None
 1.14A 2x2nA-3on6A:
undetectable		 2x2nA-3on6A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 MET A 408
PHE A 412
TYR A 357
PRO A 404
THR A  83
 None
PEG  A 495 (-4.6A)
PEG  A 495 (-4.7A)
None
None
 1.30A 2x2nA-3on6A:
undetectable		 2x2nA-3on6A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 MET A 408
PHE A 412
TYR A 357
PRO A 404
MET A 437
 None
PEG  A 495 (-4.6A)
PEG  A 495 (-4.7A)
None
None
 1.22A 2x2nB-3on6A:
undetectable		 2x2nB-3on6A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 4 LEU A 343
ASP A 346
VAL A 375
THR A 371
 None
 1.20A 3cyxB-3on6A:
undetectable		 3cyxB-3on6A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 LYS A  64
GLU A  77
TRP A  74
 None
 1.48A 3v4tH-3on6A:
undetectable		 3v4tH-3on6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 4 THR A 450
GLY A 393
ASP A 346
SER A 440
 None
 1.34A 4rfqA-3on6A:
undetectable		 4rfqA-3on6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 SER A 265
PRO A 395
PHE A 333
SER A 260
 None
 1.23A 5l1fC-3on6A:
undetectable		 5l1fC-3on6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 GLU A 390
LYS A 385
GLU A 378
PHE A 383
 EDO  A 491 (-3.6A)
None
None
None
 1.23A 5onlA-3on6A:
undetectable		 5onlA-3on6A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 ILE A 420
LYS A 467
ILE A 465
ILE A  63
LEU A  66
 None
PEG  A 495 (-2.8A)
None
None
None
 1.45A 5vkqA-3on6A:
1.4
5vkqB-3on6A:
1.4		 5vkqA-3on6A:
13.77
5vkqB-3on6A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 ILE A 420
LYS A 467
ILE A 465
ILE A  63
LEU A  66
 None
PEG  A 495 (-2.8A)
None
None
None
 1.45A 5vkqC-3on6A:
1.4
5vkqD-3on6A:
2.1		 5vkqC-3on6A:
13.77
5vkqD-3on6A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 PRO A 395
SER A 277
PHE A 333
ASP A 267
 None
 1.33A 6g6rA-3on6A:
undetectable		 6g6rA-3on6A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 GLU A 390
LYS A 385
GLU A 378
PHE A 383
 EDO  A 491 (-3.6A)
None
None
None
 1.25A 6hrjA-3on6A:
undetectable		 6hrjA-3on6A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3on6 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 THR A  87
GLU A  57
ASN A  82
 None
 0.73A 6nj9K-3on6A:
undetectable		 6nj9K-3on6A:
18.49