SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ong'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3ong UBIQUITIN-ACTIVATING
ENZYME E1-LIKE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 484
SER A 508
LEU A 504
GLY A 505
 None
 0.93A 2j2pA-3ongA:
undetectable
2j2pC-3ongA:
undetectable		 2j2pA-3ongA:
19.16
2j2pC-3ongA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3ong UBIQUITIN-ACTIVATING
ENZYME E1-LIKE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 484
SER A 508
LEU A 504
GLY A 505
 None
 0.92A 2j2pD-3ongA:
undetectable
2j2pF-3ongA:
undetectable		 2j2pD-3ongA:
19.16
2j2pF-3ongA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3ong UBIQUITIN-ACTIVATING
ENZYME E1-LIKE
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 480
LEU A 529
ILE A 465
LEU A 542
ILE A 525
 None
 1.03A 3jw3A-3ongA:
undetectable		 3jw3A-3ongA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 3ong UBIQUITIN-ACTIVATING
ENZYME E1-LIKE
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 461
ILE A 509
ARG A 484
GLY A 444
LEU A 542
 None
 1.03A 4dm8B-3ongA:
undetectable		 4dm8B-3ongA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ong UBIQUITIN-ACTIVATING
ENZYME E1-LIKE
(Saccharomyces
cerevisiae) 		4 / 7 CYH A 442
ILE A 525
PRO A 548
ILE A 550
 None
 0.98A 4w5oA-3ongA:
undetectable		 4w5oA-3ongA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ong UBIQUITIN-ACTIVATING
ENZYME E1-LIKE
(Saccharomyces
cerevisiae) 		4 / 7 CYH A 442
ILE A 525
PRO A 548
ILE A 550
 None
 0.98A 4z4eA-3ongA:
undetectable		 4z4eA-3ongA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ong UBIQUITIN-ACTIVATING
ENZYME E1-LIKE
(Saccharomyces
cerevisiae) 		4 / 7 CYH A 442
ILE A 525
PRO A 548
ILE A 550
 None
 0.99A 4z4gA-3ongA:
undetectable		 4z4gA-3ongA:
9.42