SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3onk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 147
ILE A 153
GLU A 103
ASP A 107
 None
 1.01A 1ditH-3onkA:
undetectable
1ditP-3onkA:
undetectable		 1ditH-3onkA:
22.78
1ditP-3onkA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 160
THR A  59
PHE A 105
ILE A  98
ASP A  95
 None
 1.25A 2v95A-3onkA:
undetectable		 2v95A-3onkA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  87
ALA A  90
PHE A  73
ASN A 114
THR A  40
 None
 1.03A 2w3bB-3onkA:
undetectable		 2w3bB-3onkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  87
ALA A  90
PHE A  73
ASN A 114
THR A  40
 None
 1.03A 2w3mA-3onkA:
undetectable		 2w3mA-3onkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  87
ALA A  90
PHE A  73
ASN A 114
THR A  40
 None
 1.01A 2w3mB-3onkA:
undetectable		 2w3mB-3onkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 7 GLY A 101
ILE A 106
THR A 109
ARG A 157
LEU A  97
 None
 1.23A 2xrhA-3onkA:
undetectable		 2xrhA-3onkA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 11 THR A  59
LEU A  93
LEU A  69
ILE A  72
LEU A 143
 None
 1.04A 3a50C-3onkA:
undetectable		 3a50C-3onkA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  94
LEU A  97
ILE A 116
ILE A 113
LEU A 146
 None
 1.12A 4j24A-3onkA:
undetectable		 4j24A-3onkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  94
LEU A  97
ILE A 116
ILE A 113
LEU A 146
 None
 1.10A 4j24B-3onkA:
undetectable		 4j24B-3onkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  87
ALA A  90
PHE A  73
ASN A 114
THR A  40
 None
 1.01A 4kebB-3onkA:
undetectable		 4kebB-3onkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  68
VAL A  36
ALA A  90
LEU A  94
LEU A  97
 None
 0.94A 4m11B-3onkA:
undetectable		 4m11B-3onkA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3onk EPSIN-3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  68
VAL A  36
ALA A  90
LEU A  94
LEU A  97
 None
 0.95A 4m11C-3onkA:
undetectable		 4m11C-3onkA:
14.96