SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ono'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		3 / 3 MET A   1
ASN A 106
GLN A 103
 None
 0.98A 1xoqB-3onoA:
undetectable		 1xoqB-3onoA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		5 / 9 GLY A  90
ILE A 129
VAL A  68
ILE A   3
VAL A  33
 None
 1.06A 2nnhB-3onoA:
undetectable		 2nnhB-3onoA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		4 / 4 SER A 111
GLY A  74
HIS A  50
ASP A 176
 None
 1.38A 2oxtC-3onoA:
undetectable		 2oxtC-3onoA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		4 / 8 LEU A   5
ALA A  55
LEU A  51
ALA A  77
 None
 0.83A 2vcvP-3onoA:
undetectable		 2vcvP-3onoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		3 / 3 CYH A 192
PHE A 193
PHE A 189
 None
 0.82A 3cr5X-3onoA:
undetectable		 3cr5X-3onoA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		5 / 10 VAL A  88
GLY A  86
GLN A 150
ASN A 108
GLY A 107
 None
GOL  A 215 (-3.7A)
None
GOL  A 215 (-3.5A)
GOL  A 215 (-3.6A)
 1.14A 3km6A-3onoA:
undetectable		 3km6A-3onoA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		5 / 9 VAL A  88
GLY A  86
GLN A 150
ASN A 108
GLY A 107
 None
GOL  A 215 (-3.7A)
None
GOL  A 215 (-3.5A)
GOL  A 215 (-3.6A)
 1.17A 3kmoA-3onoA:
undetectable		 3kmoA-3onoA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		5 / 9 VAL A  88
GLY A  86
GLN A 151
ASN A 108
GLY A 107
 None
GOL  A 215 (-3.7A)
None
GOL  A 215 (-3.5A)
GOL  A 215 (-3.6A)
 1.38A 3kmoA-3onoA:
undetectable		 3kmoA-3onoA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		3 / 3 SER A 186
ASP A  43
ASN A  15
 None
 0.98A 3lsfB-3onoA:
undetectable
3lsfE-3onoA:
undetectable		 3lsfB-3onoA:
22.27
3lsfE-3onoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  68
VAL A  25
LEU A  29
LEU A  22
ALA A 133
 None
 1.08A 3rr3C-3onoA:
undetectable		 3rr3C-3onoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  68
VAL A  25
LEU A  29
LEU A  22
ALA A 133
 None
 1.07A 3rr3D-3onoA:
undetectable		 3rr3D-3onoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		5 / 11 ILE A 110
ILE A   3
ILE A 129
ALA A  26
GLU A 131
 None
 0.85A 3tmzA-3onoA:
undetectable		 3tmzA-3onoA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		4 / 6 LEU A 209
TYR A 205
ILE A  53
GLY A 185
 None
 0.97A 4l39A-3onoA:
undetectable		 4l39A-3onoA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		5 / 12 PHE A 114
LEU A 112
ALA A  77
VAL A  87
PHE A  66
 None
 1.12A 4wnwB-3onoA:
undetectable		 4wnwB-3onoA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ono RIBOSE/GALACTOSE
ISOMERASE
(Vibrio
parahaemolyticus) 		4 / 6 SER A  56
HIS A  84
PRO A  85
LEU A 172
 None
 1.46A 5dzka-3onoA:
undetectable
5dzko-3onoA:
undetectable		 5dzka-3onoA:
22.82
5dzko-3onoA:
3.23