SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oon'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 3oon OUTER MEMBRANE
PROTEIN (TPN50)
(Borreliella
burgdorferi) 		3 / 3 MET A 331
LEU A 334
SER A 335
 SO4  A 401 ( 4.0A)
None
None
 0.45A 1ee2A-3oonA:
undetectable		 1ee2A-3oonA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3oon OUTER MEMBRANE
PROTEIN (TPN50)
(Borreliella
burgdorferi) 		3 / 3 LYS A 300
ILE A 304
ILE A 384
 None
 0.64A 4y0qA-3oonA:
undetectable		 4y0qA-3oonA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3oon OUTER MEMBRANE
PROTEIN (TPN50)
(Borreliella
burgdorferi) 		3 / 3 LEU A 346
PHE A 359
ILE A 347
 None
 0.75A 5dzk1-3oonA:
undetectable
5dzkF-3oonA:
undetectable
5dzkM-3oonA:
undetectable		 5dzk1-3oonA:
4.65
5dzkF-3oonA:
23.61
5dzkM-3oonA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3oon OUTER MEMBRANE
PROTEIN (TPN50)
(Borreliella
burgdorferi) 		4 / 6 SER A 335
HIS A 332
ARG A 340
GLU A 336
 None
 1.50A 5x7pB-3oonA:
2.1		 5x7pB-3oonA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3oon OUTER MEMBRANE
PROTEIN (TPN50)
(Borreliella
burgdorferi) 		4 / 6 SER A 335
HIS A 332
ARG A 340
GLU A 336
 None
 1.48A 5x7qA-3oonA:
undetectable		 5x7qA-3oonA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3oon OUTER MEMBRANE
PROTEIN (TPN50)
(Borreliella
burgdorferi) 		4 / 6 SER A 335
HIS A 332
ARG A 340
GLU A 336
 None
 1.46A 5x7rA-3oonA:
2.0		 5x7rA-3oonA:
6.87