SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3oov METHYL-ACCEPTING
CHEMOTAXIS PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		4 / 7 TYR A  83
ILE A 114
ASP A  79
PHE A  77
 None
 0.85A 1upfB-3oovA:
undetectable		 1upfB-3oovA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3oov METHYL-ACCEPTING
CHEMOTAXIS PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		4 / 6 PHE A 112
ILE A 114
GLY A  71
GLY A  70
 GOL  A 167 (-3.9A)
None
None
None
 0.73A 2qx6A-3oovA:
undetectable
2qx6B-3oovA:
undetectable		 2qx6A-3oovA:
21.15
2qx6B-3oovA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3oov METHYL-ACCEPTING
CHEMOTAXIS PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		5 / 12 SER A  47
VAL A  62
THR A  54
ILE A 104
PHE A  57
 None
 1.31A 4c49A-3oovA:
undetectable		 4c49A-3oovA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3oov METHYL-ACCEPTING
CHEMOTAXIS PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		3 / 3 ASP A 130
ARG A  33
ASP A 142
 GOL  A 167 (-3.6A)
None
None
 0.74A 4fp9A-3oovA:
undetectable		 4fp9A-3oovA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 3oov METHYL-ACCEPTING
CHEMOTAXIS PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		3 / 3 ASP A 130
ARG A  33
ASP A 142
 GOL  A 167 (-3.6A)
None
None
 0.69A 4fp9C-3oovA:
undetectable		 4fp9C-3oovA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 3oov METHYL-ACCEPTING
CHEMOTAXIS PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		3 / 3 ASP A 130
ARG A  33
ASP A 142
 GOL  A 167 (-3.6A)
None
None
 0.72A 4fp9F-3oovA:
undetectable		 4fp9F-3oovA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3oov METHYL-ACCEPTING
CHEMOTAXIS PROTEIN,
PUTATIVE
(Geobacter
sulfurreducens) 		5 / 12 LEU A 107
PHE A  57
PHE A  48
PHE A 112
THR A  74
 GOL  A 167 (-4.2A)
None
None
GOL  A 167 (-3.9A)
None
 1.31A 4ze1A-3oovA:
undetectable		 4ze1A-3oovA:
15.15