SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3op3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_D_CGED501_1 (CYTOCHROME P450 2B4)	3op3	M-PHASE INDUCER PHOSPHATASE 3 (Homo sapiens)	5 / 9	VAL A 327 PHE A 325 ILE A 341 ALA A 312 VAL A 305	None	1.01A	3me6D-3op3A: undetectable	3me6D-3op3A: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3op3	M-PHASE INDUCER PHOSPHATASE 3 (Homo sapiens)	4 / 6	ARG A 392 GLN A 350 PHE A 375 LEU A 409	SO4 A 464 (-4.1A) SO4 A 463 (-3.3A) None None	1.10A	5z86C-3op3A: undetectable 5z86J-3op3A: undetectable	5z86C-3op3A: 20.52 5z86J-3op3A: 15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3op3	M-PHASE INDUCER PHOSPHATASE 3 (Homo sapiens)	4 / 6	ARG A 392 GLN A 350 PHE A 375 LEU A 409	SO4 A 464 (-4.1A) SO4 A 463 (-3.3A) None None	1.06A	5zcpC-3op3A: undetectable 5zcpJ-3op3A: undetectable	5zcpC-3op3A: 20.52 5zcpJ-3op3A: 15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3op3	M-PHASE INDUCER PHOSPHATASE 3 (Homo sapiens)	4 / 6	ARG A 392 GLN A 350 PHE A 375 LEU A 409	SO4 A 464 (-4.1A) SO4 A 463 (-3.3A) None None	1.12A	5zcpP-3op3A: undetectable 5zcpW-3op3A: undetectable	5zcpP-3op3A: 20.52 5zcpW-3op3A: 15.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ME6_D_CGED501_1","CYTOCHROME P450 2B4","3op3","M-PHASE INDUCER PHOSPHATASE 3","Homo sapiens",5,"VAL A 327;PHE A 325;ILE A 341;ALA A 312;VAL A 305","None","1.01A","3me6D-3op3A:undetectable","3me6D-3op3A:18.43"],["5Z86_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3op3","M-PHASE INDUCER PHOSPHATASE 3","Homo sapiens",4,"ARG A 392;GLN A 350;PHE A 375;LEU A 409","SO4 A 464 (-4.1A);SO4 A 463 (-3.3A);None;None","1.10A","5z86C-3op3A:undetectable;5z86J-3op3A:undetectable","5z86C-3op3A:20.52;5z86J-3op3A:15.53"],["5ZCP_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3op3","M-PHASE INDUCER PHOSPHATASE 3","Homo sapiens",4,"ARG A 392;GLN A 350;PHE A 375;LEU A 409","SO4 A 464 (-4.1A);SO4 A 463 (-3.3A);None;None","1.06A","5zcpC-3op3A:undetectable;5zcpJ-3op3A:undetectable","5zcpC-3op3A:20.52;5zcpJ-3op3A:15.53"],["5ZCP_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3op3","M-PHASE INDUCER PHOSPHATASE 3","Homo sapiens",4,"ARG A 392;GLN A 350;PHE A 375;LEU A 409","SO4 A 464 (-4.1A);SO4 A 463 (-3.3A);None;None","1.12A","5zcpP-3op3A:undetectable;5zcpW-3op3A:undetectable","5zcpP-3op3A:20.52;5zcpW-3op3A:15.53"]]