SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3op7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.80A 1a7yA-3op7A:
undetectable		 1a7yA-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 154
PRO A 152
THR A 153
 None
 0.89A 1a7yB-3op7A:
undetectable		 1a7yB-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 ILE A 206
ILE A 159
ALA A 187
LEU A 146
ILE A 150
 None
 1.09A 1bsxA-3op7A:
undetectable		 1bsxA-3op7A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 ILE A 206
ILE A 159
ALA A 187
LEU A 146
ILE A 150
 None
 1.09A 1bsxB-3op7A:
undetectable		 1bsxB-3op7A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 5 LEU A  56
VAL A 256
LEU A 260
GLN A 263
 None
 0.78A 1fbmE-3op7A:
undetectable		 1fbmE-3op7A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 154
PRO A 152
THR A 153
 None
 0.79A 1i3wE-3op7A:
undetectable		 1i3wE-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.84A 1i3wE-3op7A:
undetectable		 1i3wE-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.77A 1i3wF-3op7A:
undetectable		 1i3wF-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 154
PRO A 152
THR A 153
 None
 0.84A 1i3wG-3op7A:
undetectable		 1i3wG-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.84A 1i3wG-3op7A:
undetectable		 1i3wG-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.85A 1i3wH-3op7A:
undetectable		 1i3wH-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 5 TRP A 232
ILE A  83
ASP A 192
ASN A 164
 None
None
LLP  A 221 ( 2.8A)
LLP  A 221 ( 3.9A)
 1.44A 1kiaD-3op7A:
2.3		 1kiaD-3op7A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 154
PRO A 152
THR A 153
 None
 0.81A 1mnvD-3op7A:
undetectable		 1mnvD-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.74A 1mnvD-3op7A:
undetectable		 1mnvD-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 4 GLY A 167
VAL A 169
TRP A 139
GLY A 138
 None
EDO  A 403 (-4.2A)
None
EDO  A 403 (-3.5A)
 0.83A 1ng8A-3op7A:
undetectable		 1ng8A-3op7A:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 4 GLY A 167
VAL A 169
TRP A 139
GLY A 138
 None
EDO  A 403 (-4.2A)
None
EDO  A 403 (-3.5A)
 0.83A 1ng8B-3op7A:
undetectable		 1ng8B-3op7A:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 154
PRO A 152
THR A 153
 None
 0.83A 1ovfB-3op7A:
undetectable		 1ovfB-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.78A 1qfiA-3op7A:
undetectable		 1qfiA-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 154
PRO A 152
THR A 153
 None
 0.86A 1unjF-3op7A:
undetectable		 1unjF-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.80A 1unjF-3op7A:
undetectable		 1unjF-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.87A 1unjL-3op7A:
undetectable		 1unjL-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.83A 1unjR-3op7A:
undetectable		 1unjR-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 153
THR A 154
PRO A 152
 None
 0.85A 1unmF-3op7A:
undetectable		 1unmF-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 LEU A 201
ASP A 171
THR A 173
LEU A 140
GLY A 138
 None
None
None
EDO  A 403 ( 4.7A)
EDO  A 403 (-3.5A)
 1.41A 1v8bA-3op7A:
2.5		 1v8bA-3op7A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 LEU A 201
ASP A 171
THR A 173
LEU A 140
GLY A 138
 None
None
None
EDO  A 403 ( 4.7A)
EDO  A 403 (-3.5A)
 1.41A 1v8bB-3op7A:
undetectable		 1v8bB-3op7A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 LEU A 201
ASP A 171
THR A 173
LEU A 140
GLY A 138
 None
None
None
EDO  A 403 ( 4.7A)
EDO  A 403 (-3.5A)
 1.43A 1v8bD-3op7A:
2.4		 1v8bD-3op7A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 TRP A 232
THR A 222
TYR A 223
 None
LLP  A 221 ( 4.3A)
None
 1.11A 2a3aA-3op7A:
undetectable		 2a3aA-3op7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 TRP A 232
THR A 222
TYR A 223
 None
LLP  A 221 ( 4.3A)
None
 1.14A 2a3aB-3op7A:
undetectable		 2a3aB-3op7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 TRP A 232
THR A 222
TYR A 223
 None
LLP  A 221 ( 4.3A)
None
 1.11A 2a3bA-3op7A:
undetectable		 2a3bA-3op7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 4 GLN A 132
GLU A 134
ILE A 133
PRO A 112
 None
 1.30A 2fcnA-3op7A:
undetectable		 2fcnA-3op7A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 ASN A  57
ASP A 259
GLN A 263
 SO4  A 401 ( 3.0A)
None
None
 0.84A 3eeyC-3op7A:
5.2		 3eeyC-3op7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 ASN A  57
ASP A 259
GLN A 263
 SO4  A 401 ( 3.0A)
None
None
 0.84A 3eeyD-3op7A:
3.9		 3eeyD-3op7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 ASN A  57
ASP A 259
GLN A 263
 SO4  A 401 ( 3.0A)
None
None
 0.84A 3eeyE-3op7A:
5.1		 3eeyE-3op7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 GLN A 365
ILE A 357
LEU A 347
VAL A 345
LEU A 333
 None
 1.09A 3gwxB-3op7A:
undetectable		 3gwxB-3op7A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 7 TYR A 174
GLU A 134
TRP A 131
LEU A 178
 None
 1.04A 3k8mB-3op7A:
undetectable		 3k8mB-3op7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 11 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.27A 4fogA-3op7A:
undetectable		 4fogA-3op7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 11 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.18A 4fogC-3op7A:
undetectable		 4fogC-3op7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 11 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.22A 4fogD-3op7A:
undetectable		 4fogD-3op7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.18A 4foxA-3op7A:
undetectable		 4foxA-3op7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 11 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.22A 4foxF-3op7A:
undetectable		 4foxF-3op7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.21A 4foxG-3op7A:
undetectable		 4foxG-3op7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 PHE A  47
TYR A  48
VAL A 261
LEU A 264
ILE A 272
 None
 1.12A 4g1bA-3op7A:
2.7		 4g1bA-3op7A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		3 / 3 THR A 154
PRO A 152
THR A 153
 None
 0.86A 4hivD-3op7A:
undetectable		 4hivD-3op7A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 ILE A 189
THR A 154
ILE A 150
LEU A 146
ILE A 157
 None
 1.09A 4kjkA-3op7A:
undetectable		 4kjkA-3op7A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 7 LEU A 124
LEU A 243
LEU A  94
ILE A 214
 None
 1.04A 4okwA-3op7A:
undetectable		 4okwA-3op7A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 8 ILE A 214
ARG A 196
LEU A 190
ILE A 206
 None
EDO  A 404 ( 4.0A)
None
None
 0.80A 4v04A-3op7A:
undetectable		 4v04A-3op7A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 7 ASN A 164
PRO A 165
PHE A 309
PHE A 349
 LLP  A 221 ( 3.9A)
None
None
None
 1.46A 4v32C-3op7A:
undetectable		 4v32C-3op7A:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 11 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.31A 5fctA-3op7A:
undetectable		 5fctA-3op7A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 LEU A 201
ASP A 171
THR A 173
LEU A 140
GLY A 138
 None
None
None
EDO  A 403 ( 4.7A)
EDO  A 403 (-3.5A)
 1.45A 5m66A-3op7A:
2.7		 5m66A-3op7A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 8 ASN A  43
PRO A  44
GLU A  34
PHE A  37
 None
 0.62A 5oh1C-3op7A:
undetectable		 5oh1C-3op7A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 LEU A 201
ASP A 171
THR A 173
LEU A 140
GLY A 138
 None
None
None
EDO  A 403 ( 4.7A)
EDO  A 403 (-3.5A)
 1.41A 5utuF-3op7A:
2.4		 5utuF-3op7A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 6 ILE A 206
ILE A 133
LEU A 140
PHE A 309
 None
None
EDO  A 403 ( 4.7A)
None
 0.93A 5vkqB-3op7A:
undetectable
5vkqC-3op7A:
undetectable		 5vkqB-3op7A:
12.79
5vkqC-3op7A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		4 / 6 ILE A 206
ILE A 133
LEU A 140
PHE A 309
 None
None
EDO  A 403 ( 4.7A)
None
 0.92A 5vkqC-3op7A:
undetectable
5vkqD-3op7A:
undetectable		 5vkqC-3op7A:
12.79
5vkqD-3op7A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.26A 6r2eA-3op7A:
undetectable		 6r2eA-3op7A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 10 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.26A 6r2eB-3op7A:
undetectable		 6r2eB-3op7A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 10 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.24A 6r2eC-3op7A:
undetectable		 6r2eC-3op7A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 10 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.25A 6r2eD-3op7A:
undetectable		 6r2eD-3op7A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 11 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.20A 6r2eF-3op7A:
undetectable		 6r2eF-3op7A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 11 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.30A 6r2eG-3op7A:
undetectable		 6r2eG-3op7A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 3op7 AMINOTRANSFERASE
CLASS I AND II
(Streptococcus
suis) 		5 / 12 ILE A  83
TRP A 232
LEU A 219
ASP A 259
GLY A  63
 None
 1.28A 6r2eH-3op7A:
undetectable		 6r2eH-3op7A:
24.69