SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3opu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.17A 1kifA-3opuA:
undetectable		 1kifA-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.17A 1kifB-3opuA:
undetectable		 1kifB-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.17A 1kifC-3opuA:
undetectable		 1kifC-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.17A 1kifD-3opuA:
undetectable		 1kifD-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.17A 1kifE-3opuA:
undetectable		 1kifE-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.17A 1kifF-3opuA:
undetectable		 1kifF-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.17A 1kifG-3opuA:
undetectable		 1kifG-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.16A 1kifH-3opuA:
undetectable		 1kifH-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 3opu SPAP
(Streptococcus
mutans) 		5 / 11 TYR A1205
ILE A1312
PRO A1260
ASN A1321
VAL A1323
 None
 1.29A 1mrlA-3opuA:
undetectable
1mrlB-3opuA:
undetectable		 1mrlA-3opuA:
22.53
1mrlB-3opuA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.24A 1ve9A-3opuA:
undetectable		 1ve9A-3opuA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3opu SPAP
(Streptococcus
mutans) 		5 / 12 ILE A1330
GLY A1366
LEU A1363
VAL A1398
ILE A1435
 None
 1.25A 1zq9A-3opuA:
undetectable		 1zq9A-3opuA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3opu SPAP
(Streptococcus
mutans) 		4 / 7 THR A1278
VAL A1234
GLY A1233
ASP A1225
 None
 0.91A 2a1mA-3opuA:
undetectable		 2a1mA-3opuA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3opu SPAP
(Streptococcus
mutans) 		4 / 8 THR A1278
VAL A1234
GLY A1233
ASP A1225
 None
 0.88A 2a1oA-3opuA:
undetectable		 2a1oA-3opuA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.20A 2du8G-3opuA:
undetectable		 2du8G-3opuA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3opu SPAP
(Streptococcus
mutans) 		4 / 5 TYR A1361
ILE A1457
ARG A1461
GLY A1389
 None
 1.22A 2du8J-3opuA:
undetectable		 2du8J-3opuA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 3opu SPAP
(Streptococcus
mutans) 		3 / 3 TYR A1379
TYR A1471
GLY A1366
 None
 0.71A 3eteB-3opuA:
undetectable
3eteD-3opuA:
undetectable
3eteF-3opuA:
undetectable		 3eteB-3opuA:
23.67
3eteD-3opuA:
23.67
3eteF-3opuA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 3opu SPAP
(Streptococcus
mutans) 		5 / 12 VAL A1234
LEU A1286
VAL A1231
ILE A1284
THR A1282
 None
 1.38A 3frqA-3opuA:
undetectable		 3frqA-3opuA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3opu SPAP
(Streptococcus
mutans) 		5 / 12 PRO A1342
ASN A1347
TYR A1456
GLU A1454
ILE A1364
 None
 1.46A 3q5pA-3opuA:
undetectable		 3q5pA-3opuA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3opu SPAP
(Streptococcus
mutans) 		5 / 11 PRO A1342
ASN A1347
TYR A1456
GLU A1454
ILE A1364
 None
 1.42A 3q5rA-3opuA:
undetectable		 3q5rA-3opuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3opu SPAP
(Streptococcus
mutans) 		3 / 3 TYR A1382
THR A1474
THR A1434
 None
 0.70A 5aoxB-3opuA:
undetectable		 5aoxB-3opuA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3opu SPAP
(Streptococcus
mutans) 		3 / 3 TYR A1382
THR A1474
THR A1434
 None
 0.75A 5aoxE-3opuA:
undetectable		 5aoxE-3opuA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3opu SPAP
(Streptococcus
mutans) 		4 / 7 ILE A1364
VAL A1445
ILE A1368
PHE A1441
 None
 0.97A 5hieC-3opuA:
undetectable		 5hieC-3opuA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3opu SPAP
(Streptococcus
mutans) 		4 / 8 ALA A1174
PHE A1377
THR A1177
GLY A1477
 None
 0.93A 5v0vA-3opuA:
undetectable		 5v0vA-3opuA:
17.38