SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3opx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 162
LEU A 120
LEU A 159
THR A 140
LEU A  41
 None
None
None
U5P  A 265 (-3.7A)
None
 1.19A 1jipA-3opxA:
undetectable		 1jipA-3opxA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 167
ASP A  18
LYS A 185
 None
 1.01A 1lqtB-3opxA:
2.3		 1lqtB-3opxA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 167
ASP A  18
LYS A 185
 None
 1.00A 1lquB-3opxA:
2.0		 1lquB-3opxA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		4 / 5 ILE A  86
LEU A  84
ASP A 167
ALA A  97
 None
U5P  A 265 (-4.9A)
None
None
 0.96A 2opxA-3opxA:
2.4		 2opxA-3opxA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 208
ILE A 244
LEU A 247
ILE A 241
 None
 0.81A 2q83A-3opxA:
undetectable		 2q83A-3opxA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		3 / 3 TYR A  79
TYR A 100
ILE A  86
 U5P  A 265 (-4.7A)
None
None
 0.83A 3eteA-3opxA:
undetectable
3eteB-3opxA:
undetectable		 3eteA-3opxA:
18.92
3eteB-3opxA:
18.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		4 / 5 LEU A  51
SER A  55
LEU A 108
PRO A 109
 None
 0.18A 3onnA-3opxA:
43.3		 3onnA-3opxA:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		4 / 5 GLY A 205
LYS A 206
GLU A 209
PRO A 235
 None
 0.24A 3onnA-3opxA:
43.3		 3onnA-3opxA:
99.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		4 / 8 TYR A 165
LEU A 174
CYH A 176
TYR A 168
 None
 1.33A 3po7A-3opxA:
undetectable		 3po7A-3opxA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		5 / 9 PHE A 200
ALA A 198
PHE A 183
ALA A 186
THR A 164
 None
 1.32A 3t3sA-3opxA:
undetectable		 3t3sA-3opxA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 185
GLU A 189
TRP A 137
 None
 1.36A 3v4tH-3opxA:
undetectable		 3v4tH-3opxA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  35
LEU A 136
VAL A 251
LEU A 254
SER A 130
 None
 1.44A 4po0A-3opxA:
undetectable		 4po0A-3opxA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  70
ASN A  75
PHE A  59
 None
 0.71A 5dsgB-3opxA:
undetectable		 5dsgB-3opxA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 159
TYR A  42
PRO A 116
ILE A 118
 None
 1.20A 5esgA-3opxA:
1.8		 5esgA-3opxA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 3opx PROTEIN SSM1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 120
MET A 123
ILE A 201
THR A  46
LEU A 222
 None
 1.33A 5ienA-3opxA:
undetectable		 5ienA-3opxA:
24.02