SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3opz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3opz HEAVY CHAIN OF THE
FAB FRAGMENT OF
IMMUNOGLOBULIN G
(Mus
musculus) 		5 / 11 VAL H 117
LEU H  83
LEU H 115
THR H  87
GLU H  46
 None
 1.22A 1mmtA-3opzH:
undetectable		 1mmtA-3opzH:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3opz HEAVY CHAIN OF THE
FAB FRAGMENT OF
IMMUNOGLOBULIN G
(Mus
musculus) 		5 / 12 TYR H 181
ALA H 207
ILE H  93
THR H 116
LEU H  11
 None
 1.25A 2bjfA-3opzH:
undetectable		 2bjfA-3opzH:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3opz HEAVY CHAIN OF THE
FAB FRAGMENT OF
IMMUNOGLOBULIN G
(Mus
musculus) 		3 / 3 TYR H 108
HIS H 100
ARG H  98
 None
 0.94A 4htfA-3opzH:
undetectable		 4htfA-3opzH:
22.59