SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_D_DVAD8_0 (GRAMICIDIN D)	3oq2	CRISPR-ASSOCIATED PROTEIN CAS2 (Desulfovibrio vulgaris)	3 / 3	VAL A 48 VAL A 9 TRP A 81	None	0.96A	1w5uC-3oq2A: undetectable 1w5uD-3oq2A: undetectable	1w5uC-3oq2A: 11.70 1w5uD-3oq2A: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_D_DVAD8_0 (GRAMICIDIN D)	3oq2	CRISPR-ASSOCIATED PROTEIN CAS2 (Desulfovibrio vulgaris)	3 / 3	VAL A 48 VAL A 9 TRP A 81	None	0.90A	3l8lC-3oq2A: undetectable 3l8lD-3oq2A: undetectable	3l8lC-3oq2A: 11.70 3l8lD-3oq2A: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JM4_A_BEZA301_0 (14-3-3 PROTEIN ZETA/DELTA)	3oq2	CRISPR-ASSOCIATED PROTEIN CAS2 (Desulfovibrio vulgaris)	4 / 5	PHE A 45 ILE A 29 GLN A 34 ARG A 39	None None None SO4 A 107 (-3.0A)	1.35A	5jm4A-3oq2A: undetectable	5jm4A-3oq2A: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JM4_B_BEZB301_0 (14-3-3 PROTEIN ZETA/DELTA)	3oq2	CRISPR-ASSOCIATED PROTEIN CAS2 (Desulfovibrio vulgaris)	4 / 4	PHE A 45 ILE A 29 GLN A 34 ARG A 39	None None None SO4 A 107 (-3.0A)	1.31A	5jm4B-3oq2A: undetectable	5jm4B-3oq2A: 19.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1W5U_D_DVAD8_0","GRAMICIDIN D","3oq2","CRISPR-ASSOCIATED PROTEIN CAS2","Desulfovibrio vulgaris",3,"VAL A  48;VAL A   9;TRP A  81","None","0.96A","1w5uC-3oq2A:undetectable;1w5uD-3oq2A:undetectable","1w5uC-3oq2A:11.70;1w5uD-3oq2A:11.70"],["3L8L_D_DVAD8_0","GRAMICIDIN D","3oq2","CRISPR-ASSOCIATED PROTEIN CAS2","Desulfovibrio vulgaris",3,"VAL A  48;VAL A   9;TRP A  81","None","0.90A","3l8lC-3oq2A:undetectable;3l8lD-3oq2A:undetectable","3l8lC-3oq2A:11.70;3l8lD-3oq2A:11.70"],["5JM4_A_BEZA301_0","14-3-3 PROTEIN ZETA\/DELTA","3oq2","CRISPR-ASSOCIATED PROTEIN CAS2","Desulfovibrio vulgaris",4,"PHE A  45;ILE A  29;GLN A  34;ARG A  39","None;None;None;SO4 A 107 (-3.0A)","1.35A","5jm4A-3oq2A:undetectable","5jm4A-3oq2A:19.37"],["5JM4_B_BEZB301_0","14-3-3 PROTEIN ZETA\/DELTA","3oq2","CRISPR-ASSOCIATED PROTEIN CAS2","Desulfovibrio vulgaris",4,"PHE A  45;ILE A  29;GLN A  34;ARG A  39","None;None;None;SO4 A 107 (-3.0A)","1.31A","5jm4B-3oq2A:undetectable","5jm4B-3oq2A:19.37"]]