SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		5 / 11 VAL B 221
TYR B 135
LEU B 183
ILE B 185
ASP B 192
 None
 1.40A 1t6zB-3oq3B:
undetectable		 1t6zB-3oq3B:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 3oq3 INTERFERON ALPHA-5
(Mus
musculus) 		3 / 3 TRP A 149
ALA A  14
VAL A  19
 None
 0.97A 1w5uA-3oq3A:
undetectable
1w5uB-3oq3A:
undetectable		 1w5uA-3oq3A:
9.02
1w5uB-3oq3A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		5 / 12 GLY B  34
GLY B  33
VAL B 108
LEU B  58
SER B  59
 None
 1.03A 1ya4C-3oq3B:
undetectable		 1ya4C-3oq3B:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 3oq3 INTERFERON ALPHA-5
(Mus
musculus) 		3 / 3 TRP A 149
ALA A  14
VAL A  19
 None
 0.89A 2izqC-3oq3A:
undetectable
2izqD-3oq3A:
undetectable		 2izqC-3oq3A:
9.02
2izqD-3oq3A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3oq3 INTERFERON ALPHA-5
IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Mus
musculus;
Ectromelia
virus) 		5 / 12 ILE A  67
ILE B 272
LEU A  60
VAL A 156
LEU A  18
 None
 1.21A 2qo5A-3oq3A:
undetectable		 2qo5A-3oq3A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3oq3 INTERFERON ALPHA-5
IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Mus
musculus;
Ectromelia
virus) 		4 / 7 LEU A  17
ASP B 259
SER A  84
THR A  80
 None
 1.06A 3dzgB-3oq3A:
undetectable		 3dzgB-3oq3A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3oq3 INTERFERON ALPHA-5
(Mus
musculus) 		4 / 6 LEU A 152
SER A 155
LEU A 159
LEU A  15
 None
 1.05A 3f33A-3oq3A:
4.0		 3f33A-3oq3A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 3oq3 INTERFERON ALPHA-5
(Mus
musculus) 		3 / 3 TRP A 149
ALA A  14
VAL A  19
 None
 1.00A 3l8lA-3oq3A:
undetectable
3l8lB-3oq3A:
undetectable		 3l8lA-3oq3A:
9.02
3l8lB-3oq3A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 3oq3 INTERFERON ALPHA-5
(Mus
musculus) 		3 / 3 TRP A 149
ALA A  14
VAL A  19
 None
 0.94A 3l8lC-3oq3A:
undetectable
3l8lD-3oq3A:
undetectable		 3l8lC-3oq3A:
9.02
3l8lD-3oq3A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		4 / 6 ILE B   7
ASP B  22
ILE B 119
GLY B  34
 None
 0.98A 3n3iA-3oq3B:
undetectable		 3n3iA-3oq3B:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		3 / 3 TYR B 303
TYR B 308
GLU B 297
 None
 0.94A 3pfgA-3oq3B:
undetectable		 3pfgA-3oq3B:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		4 / 7 TYR B 157
GLN B 178
TYR B 196
PRO B 128
 None
 1.22A 3ugrA-3oq3B:
undetectable		 3ugrA-3oq3B:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		3 / 3 GLU B   4
ARG B  61
HIS B  60
 None
 0.56A 4kf9A-3oq3B:
undetectable		 4kf9A-3oq3B:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		4 / 4 HIS B 140
GLU B 136
HIS B 227
LEU B 262
 ZN  A 167 (-3.3A)
None
None
None
 1.42A 4m2rA-3oq3B:
undetectable		 4m2rA-3oq3B:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
INTERFERON ALPHA-5
(Ectromelia
virus;
Mus
musculus) 		4 / 8 ASN A  66
MET B  36
GLU B  54
GLU A  59
 None
 1.04A 4mj8A-3oq3A:
undetectable
4mj8C-3oq3A:
undetectable		 4mj8A-3oq3A:
22.45
4mj8C-3oq3A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
INTERFERON ALPHA-5
(Ectromelia
virus;
Mus
musculus) 		4 / 8 ASN A  66
MET B  36
GLU B  54
GLU A  59
 None
 1.06A 4mj8B-3oq3A:
undetectable
4mj8C-3oq3A:
undetectable		 4mj8B-3oq3A:
22.45
4mj8C-3oq3A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3oq3 INTERFERON ALPHA-5
(Mus
musculus) 		5 / 12 PHE A  38
GLY A  37
ALA A 119
VAL A 120
PHE A 124
 None
 1.15A 4u8vB-3oq3A:
undetectable		 4u8vB-3oq3A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		3 / 3 GLY B 242
THR B 300
ASN B 298
 None
 0.65A 5odiG-3oq3B:
undetectable		 5odiG-3oq3B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
INTERFERON ALPHA-5
(Ectromelia
virus;
Mus
musculus) 		4 / 8 ILE B 272
VAL A 156
LEU A  15
THR A  16
 None
 0.75A 5og9A-3oq3B:
undetectable		 5og9A-3oq3B:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
(Ectromelia
virus) 		5 / 9 VAL B  85
GLY B  88
ILE B 119
LEU B 105
ARG B  84
 None
 1.34A 6c2mC-3oq3B:
undetectable		 6c2mC-3oq3B:
14.10