SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXD_B_RWFB2001_1
(SERUM ALBUMIN)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 10 PHE A 352
ARG A 156
LEU A 144
ILE A 152
ALA A 153
 None
 1.00A 2bxdB-3oqbA:
0.0		 2bxdB-3oqbA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		4 / 6 ARG A 156
VAL A 209
LEU A 149
ALA A 153
 None
 1.09A 2e1qA-3oqbA:
undetectable		 2e1qA-3oqbA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		3 / 3 LEU A 146
LEU A 323
MET A 294
 None
 0.60A 2itzA-3oqbA:
undetectable		 2itzA-3oqbA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		3 / 3 LEU A 290
LEU A 323
MET A 294
 None
 0.83A 2itzA-3oqbA:
undetectable		 2itzA-3oqbA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 12 ILE A 152
LEU A 155
GLY A 159
ALA A 286
VAL A 287
 None
 0.85A 2oc8A-3oqbA:
undetectable		 2oc8A-3oqbA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		4 / 8 TYR A 111
PHE A  88
GLN A 336
PHE A 333
 None
 0.98A 2weyB-3oqbA:
undetectable		 2weyB-3oqbA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 9 THR A 353
GLY A 138
GLY A 357
ARG A  96
ILE A 116
 None
 1.45A 2y7wA-3oqbA:
2.6		 2y7wA-3oqbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		4 / 8 ARG A 156
VAL A 209
LEU A 149
ALA A 153
 None
 0.99A 3ax7A-3oqbA:
undetectable		 3ax7A-3oqbA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 11 LEU A  24
GLY A  13
ALA A  90
ILE A  10
ILE A  28
 None
 1.10A 3ebzB-3oqbA:
undetectable		 3ebzB-3oqbA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 12 THR A 276
GLY A 169
ASN A 262
ILE A 152
GLY A 148
 None
 0.94A 3eeyA-3oqbA:
4.6		 3eeyA-3oqbA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 12 THR A 276
GLY A 169
ASN A 262
ILE A 152
GLY A 148
 None
 0.94A 3eeyB-3oqbA:
4.4		 3eeyB-3oqbA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 12 THR A 276
GLY A 169
ASN A 262
ILE A 152
GLY A 148
 None
 0.94A 3eeyF-3oqbA:
4.4		 3eeyF-3oqbA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 12 THR A 276
GLY A 169
ASN A 262
ILE A 152
GLY A 148
 None
 0.95A 3eeyH-3oqbA:
4.2		 3eeyH-3oqbA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 12 THR A 276
GLY A 169
ASN A 262
ILE A 152
GLY A 148
 None
 0.94A 3eeyI-3oqbA:
3.8		 3eeyI-3oqbA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 9 ARG A 168
ILE A 258
LEU A 210
ARG A 271
GLU A 170
 None
 1.32A 3nxuB-3oqbA:
undetectable		 3nxuB-3oqbA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 11 MET A 263
ILE A 199
VAL A 203
HIS A 260
ILE A 261
 None
 1.33A 3rf4A-3oqbA:
undetectable
3rf4C-3oqbA:
undetectable		 3rf4A-3oqbA:
17.11
3rf4C-3oqbA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 11 HIS A 260
ILE A 261
MET A 263
ILE A 199
VAL A 203
 None
 1.29A 3rf4A-3oqbA:
undetectable
3rf4B-3oqbA:
undetectable		 3rf4A-3oqbA:
17.11
3rf4B-3oqbA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 11 HIS A 260
ILE A 261
MET A 263
ILE A 199
VAL A 203
 None
 1.33A 3rf4B-3oqbA:
undetectable
3rf4C-3oqbA:
undetectable		 3rf4B-3oqbA:
17.11
3rf4C-3oqbA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		4 / 7 ARG A 156
VAL A 209
LEU A 149
ALA A 153
 None
 0.98A 3uniA-3oqbA:
undetectable		 3uniA-3oqbA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		4 / 8 GLY A  13
VAL A  14
PHE A  87
ILE A  10
 None
 0.88A 4fglD-3oqbA:
4.0		 4fglD-3oqbA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		4 / 7 GLY A  13
VAL A  14
PHE A  87
ILE A  10
 None
 0.86A 4fglC-3oqbA:
3.0		 4fglC-3oqbA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		4 / 8 GLY A 236
GLN A 235
TYR A 239
SER A 187
 None
 1.01A 4ws1A-3oqbA:
undetectable		 4ws1A-3oqbA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		4 / 4 CYH A 112
LEU A 354
LEU A 100
ALA A 130
 None
 1.00A 5hpuA-3oqbA:
undetectable
5hpuB-3oqbA:
undetectable		 5hpuA-3oqbA:
4.32
5hpuB-3oqbA:
5.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 10 GLY A 197
GLY A 196
ILE A 198
ALA A 243
THR A 226
 None
 0.92A 6e5zA-3oqbA:
6.2		 6e5zA-3oqbA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 3oqb OXIDOREDUCTASE
(Bradyrhizobium
diazoefficiens) 		5 / 12 THR A  92
PHE A  87
VAL A 110
VAL A 135
TYR A 350
 None
 1.40A 6hu9N-3oqbA:
undetectable		 6hu9N-3oqbA:
21.43