SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oqc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 6 LEU A 205
LEU A 215
LEU A  33
LEU A  36
 None
 0.87A 1errA-3oqcA:
undetectable		 1errA-3oqcA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 8 SER A 298
VAL A 348
SER A 345
ASN A 451
 None
 1.20A 1hwiB-3oqcA:
undetectable		 1hwiB-3oqcA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 8 SER A 298
VAL A 348
SER A 345
ASN A 451
 None
 1.18A 1hwkA-3oqcA:
undetectable		 1hwkA-3oqcA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 8 SER A 298
VAL A 348
SER A 345
ASN A 451
 None
 1.18A 1hwkC-3oqcA:
undetectable		 1hwkC-3oqcA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 8 SER A 298
VAL A 348
SER A 345
ASN A 451
 None
 1.16A 1hwkD-3oqcA:
undetectable		 1hwkD-3oqcA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		3 / 3 ASP A 250
HIS A 280
ASP A 285
 None
 0.79A 1nw5A-3oqcA:
undetectable		 1nw5A-3oqcA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 4 LEU A 260
PRO A 441
ILE A 416
LEU A 415
 None
 1.14A 1ya4C-3oqcA:
undetectable		 1ya4C-3oqcA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 6 ILE A 316
PRO A 455
SER A 360
MET A 390
 None
 1.33A 2qd3B-3oqcA:
undetectable		 2qd3B-3oqcA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 7 TYR A 282
HIS A 420
GLN A 300
VAL A 348
 None
 1.07A 3jwqC-3oqcA:
undetectable		 3jwqC-3oqcA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		3 / 3 ARG A   6
GLU A 246
ASN A 108
 None
 0.85A 4imaD-3oqcA:
undetectable		 4imaD-3oqcA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		3 / 3 ARG A   6
GLU A 246
ASN A 108
 None
 0.82A 4ip7D-3oqcA:
undetectable		 4ip7D-3oqcA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		4 / 7 VAL A 204
PHE A 235
HIS A 223
GLU A 221
 None
 1.32A 5ad9A-3oqcA:
undetectable
5ad9B-3oqcA:
undetectable		 5ad9A-3oqcA:
20.43
5ad9B-3oqcA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3oqc UFM1-SPECIFIC
PROTEASE 2
(Mus
musculus) 		5 / 12 ASP A 143
ILE A   7
ARG A   6
SER A  52
ARG A  48
 None
 1.36A 5il1A-3oqcA:
undetectable		 5il1A-3oqcA:
18.56