SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 3oql TENA HOMOLOG
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 4 HIS A  84
LEU A 221
LEU A 225
LEU A 206
 None
 0.91A 1a4lD-3oqlA:
undetectable		 1a4lD-3oqlA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3oql TENA HOMOLOG
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 HIS A 194
VAL A  64
SER A 232
LEU A 134
THR A 162
 None
 1.24A 1dmyA-3oqlA:
undetectable		 1dmyA-3oqlA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3oql TENA HOMOLOG
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 GLU A  87
ILE A 208
CYH A 210
LEU A  24
MET A 151
 None
 1.29A 3adsA-3oqlA:
undetectable		 3adsA-3oqlA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 3oql TENA HOMOLOG
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  61
MET A  54
MET A  44
THR A 162
ILE A 158
 None
 1.13A 4oktA-3oqlA:
undetectable		 4oktA-3oqlA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3oql TENA HOMOLOG
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 MET A  44
GLN A  43
ARG A  45
 None
 1.02A 5ewzB-3oqlA:
2.7		 5ewzB-3oqlA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 3oql TENA HOMOLOG
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 TYR A 233
LYS A  32
THR A 154
ILE A 209
 None
 1.07A 5jhdE-3oqlA:
undetectable
5jhdG-3oqlA:
undetectable		 5jhdE-3oqlA:
20.36
5jhdG-3oqlA:
17.62