SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3or5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 PRO A 139
SER A 141
PHE A 163
ILE A 154
 None
 0.93A 2y7kA-3or5A:
undetectable		 2y7kA-3or5A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 ARG A 158
ASP A  76
ASP A 162
 None
 0.90A 3jayA-3or5A:
undetectable		 3jayA-3or5A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 PHE A  91
ASP A  76
ILE A 154
VAL A 143
 None
 0.89A 3p6hA-3or5A:
undetectable		 3p6hA-3or5A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 ALA A  35
ILE A  94
ILE A 144
VAL A  60
VAL A  92
 None
 0.92A 4nkxA-3or5A:
undetectable		 4nkxA-3or5A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		4 / 4 GLU A 122
PRO A 121
ILE A 124
LEU A 123
 None
 1.07A 5m45A-3or5A:
undetectable		 5m45A-3or5A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		4 / 4 GLU A 122
PRO A 121
ILE A 124
LEU A 123
 None
 1.14A 5m45D-3or5A:
undetectable		 5m45D-3or5A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		4 / 4 GLU A 122
PRO A 121
ILE A 124
LEU A 123
 None
 1.05A 5m45G-3or5A:
undetectable		 5m45G-3or5A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		4 / 4 GLU A 122
PRO A 121
ILE A 124
LEU A 123
 None
 1.14A 5m45J-3or5A:
undetectable		 5m45J-3or5A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 LEU A 123
ILE A  94
TYR A  58
 None
 0.60A 5uunB-3or5A:
undetectable		 5uunB-3or5A:
22.87