SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ors'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 1.00A 1hxbB-3orsA:
undetectable		 1hxbB-3orsA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 1.14A 1sduB-3orsA:
undetectable		 1sduB-3orsA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 11 VAL A  81
ALA A  74
LEU A  69
MET A  44
PHE A  47
 None
 1.20A 1uduA-3orsA:
undetectable		 1uduA-3orsA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 1.08A 2o4kA-3orsA:
undetectable		 2o4kA-3orsA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 11 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 1.01A 3ekxB-3orsA:
undetectable		 3ekxB-3orsA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 9 ALA A  67
ILE A  86
GLY A  93
ILE A  94
THR A 111
 None
 0.94A 3el4B-3orsA:
undetectable		 3el4B-3orsA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		4 / 8 ALA A  67
GLY A  93
ILE A  94
THR A 111
 None
 0.67A 3el9A-3orsA:
undetectable		 3el9A-3orsA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 10 ALA A  67
ILE A  86
GLY A  93
ILE A  94
THR A 111
 None
 0.90A 3el9B-3orsA:
undetectable		 3el9B-3orsA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 10 GLY A  64
ALA A  63
ASP A  12
GLY A 115
ILE A 114
 None
 1.05A 3el9B-3orsA:
undetectable		 3el9B-3orsA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 9 GLY A  64
ALA A  63
ASP A  12
GLY A 115
ILE A 114
 None
 1.08A 3gguB-3orsA:
undetectable		 3gguB-3orsA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 0.97A 3ndxA-3orsA:
undetectable		 3ndxA-3orsA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 9 GLY A  64
ALA A  63
ASP A  12
GLY A 115
ILE A 114
 None
 0.90A 3ogpA-3orsA:
undetectable		 3ogpA-3orsA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 0.93A 3tkgB-3orsA:
undetectable		 3tkgB-3orsA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 1.02A 3tkgC-3orsA:
undetectable		 3tkgC-3orsA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 0.99A 3tkgD-3orsA:
undetectable		 3tkgD-3orsA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 9 GLY A  64
ALA A  63
ASP A  12
GLY A 115
ILE A 114
 None
 1.06A 4dqcB-3orsA:
undetectable		 4dqcB-3orsA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		6 / 11 ALA A  67
ILE A  86
GLY A  93
ILE A  94
THR A 111
ILE A 100
 None
 1.07A 4njtC-3orsA:
undetectable		 4njtC-3orsA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
THR A 111
 None
 0.98A 4njuA-3orsA:
undetectable		 4njuA-3orsA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
THR A 111
 None
 0.97A 4njuC-3orsA:
undetectable		 4njuC-3orsA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 11 SER A  19
THR A 112
THR A 111
GLY A 115
ALA A 119
 None
 1.11A 4qvwV-3orsA:
undetectable
4qvwb-3orsA:
undetectable		 4qvwV-3orsA:
21.34
4qvwb-3orsA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 11 SER A  19
THR A 112
THR A 111
GLY A 115
ALA A 119
 None
 1.11A 4qvwH-3orsA:
undetectable
4qvwN-3orsA:
undetectable		 4qvwH-3orsA:
21.34
4qvwN-3orsA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 11 SER A  19
THR A 112
THR A 111
GLY A 115
ALA A 119
 None
 1.11A 4qw0V-3orsA:
undetectable
4qw0b-3orsA:
undetectable		 4qw0V-3orsA:
21.34
4qw0b-3orsA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 11 SER A  19
THR A 112
THR A 111
GLY A 115
ALA A 119
 None
 1.11A 4qw0H-3orsA:
undetectable
4qw0N-3orsA:
undetectable		 4qw0H-3orsA:
21.34
4qw0N-3orsA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		6 / 11 ALA A  67
ILE A  86
GLY A  93
ILE A  94
THR A 111
ILE A 100
 None
 1.20A 4rvjA-3orsA:
undetectable		 4rvjA-3orsA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		6 / 11 ALA A  67
ILE A  86
GLY A  93
ILE A  94
THR A 111
ILE A 100
 None
 1.20A 4rvjC-3orsA:
undetectable		 4rvjC-3orsA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 9 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 1.18A 5kr0A-3orsA:
undetectable		 5kr0A-3orsA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 10 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 1.03A 5kr1A-3orsA:
undetectable		 5kr1A-3orsA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 1.03A 6difA-3orsA:
undetectable		 6difA-3orsA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 3ors N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE
(Staphylococcus
aureus) 		5 / 12 ALA A  67
ILE A  86
GLY A  93
ILE A  94
ILE A 100
 None
 0.90A 6difB-3orsA:
undetectable		 6difB-3orsA:
18.67