SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_C_SAMC803_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	3oru	DUF1989 FAMILY PROTEIN (Ruegeria sp. TM1040)	5 / 11	GLY A 73 SER A 101 ARG A 103 TYR A 78 PHE A 70	None	1.40A	2h21C-3oruA: undetectable	2h21C-3oruA: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEY_B_EV1B1771_1 (CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE)	3oru	DUF1989 FAMILY PROTEIN (Ruegeria sp. TM1040)	4 / 8	LEU A 108 VAL A 56 ILE A 46 PHE A 67	None	0.95A	2weyB-3oruA: undetectable	2weyB-3oruA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_C_VIVC301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	3oru	DUF1989 FAMILY PROTEIN (Ruegeria sp. TM1040)	6 / 12	TRP A 168 VAL A 192 LEU A 111 ALA A 69 PHE A 67 VAL A 200	None	1.43A	3w67C-3oruA: undetectable	3w67C-3oruA: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N09_A_ADNA401_2 (ADENOSINE KINASE)	3oru	DUF1989 FAMILY PROTEIN (Ruegeria sp. TM1040)	4 / 4	LEU A 84 SER A 101 LEU A 108 LEU A 88	None	1.10A	4n09A-3oruA: undetectable	4n09A-3oruA: 20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB5_B_010B607_0 (HNL ISOENZYME 5)	3oru	DUF1989 FAMILY PROTEIN (Ruegeria sp. TM1040)	5 / 10	ALA A 153 ARG A 47 ALA A 150 VAL A 203 VAL A 201	None	1.34A	5eb5B-3oruA: undetectable	5eb5B-3oruA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GWK_F_EVPF102_1 (DNA TOPOISOMERASE 2-ALPHA)	3oru	DUF1989 FAMILY PROTEIN (Ruegeria sp. TM1040)	4 / 5	GLY A 15 ASP A 14 ARG A 148 MET A 209	None CL A 301 ( 4.6A) None None	1.06A	5gwkA-3oruA: undetectable	5gwkA-3oruA: 14.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2H21_C_SAMC803_0","RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE\/OXYGENASE","3oru","DUF1989 FAMILY PROTEIN","Ruegeria sp. TM1040",5,"GLY A  73;SER A 101;ARG A 103;TYR A  78;PHE A  70","None","1.40A","2h21C-3oruA:undetectable","2h21C-3oruA:19.76"],["2WEY_B_EV1B1771_1","CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE","3oru","DUF1989 FAMILY PROTEIN","Ruegeria sp. TM1040",4,"LEU A 108;VAL A  56;ILE A  46;PHE A  67","None","0.95A","2weyB-3oruA:undetectable","2weyB-3oruA:19.54"],["3W67_C_VIVC301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","3oru","DUF1989 FAMILY PROTEIN","Ruegeria sp. TM1040",6,"TRP A 168;VAL A 192;LEU A 111;ALA A  69;PHE A  67;VAL A 200","None","1.43A","3w67C-3oruA:undetectable","3w67C-3oruA:22.95"],["4N09_A_ADNA401_2","ADENOSINE KINASE","3oru","DUF1989 FAMILY PROTEIN","Ruegeria sp. TM1040",4,"LEU A  84;SER A 101;LEU A 108;LEU A  88","None","1.10A","4n09A-3oruA:undetectable","4n09A-3oruA:20.80"],["5EB5_B_010B607_0","HNL ISOENZYME 5","3oru","DUF1989 FAMILY PROTEIN","Ruegeria sp. TM1040",5,"ALA A 153;ARG A  47;ALA A 150;VAL A 203;VAL A 201","None","1.34A","5eb5B-3oruA:undetectable","5eb5B-3oruA:18.53"],["5GWK_F_EVPF102_1","DNA TOPOISOMERASE 2-ALPHA","3oru","DUF1989 FAMILY PROTEIN","Ruegeria sp. TM1040",4,"GLY A  15;ASP A  14;ARG A 148;MET A 209","None; CL A 301 ( 4.6A);None;None","1.06A","5gwkA-3oruA:undetectable","5gwkA-3oruA:14.92"]]