SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3os7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 LEU A  30
VAL A  39
VAL A 118
VAL A 132
 None
 0.92A 1iwiA-3os7A:
undetectable		 1iwiA-3os7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 PHE A  87
PRO A 178
PHE A  96
PHE A 146
 None
None
PG4  A 400 ( 3.9A)
PG4  A 400 (-4.0A)
 1.29A 1lquA-3os7A:
undetectable		 1lquA-3os7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		5 / 10 GLY A 182
ILE A 107
GLY A 109
ILE A 111
PRO A  68
 None
 1.00A 1sh9B-3os7A:
undetectable		 1sh9B-3os7A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 HIS A 184
ALA A 186
GLY A  72
ASN A  38
 TLA  A 401 (-3.9A)
None
None
None
 0.75A 2c49B-3os7A:
undetectable		 2c49B-3os7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		5 / 10 GLY A 182
ILE A 107
GLY A 109
ILE A 111
PRO A  68
 None
 0.94A 2r5qD-3os7A:
undetectable		 2r5qD-3os7A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 MET A 291
VAL A 202
GLU A 300
 None
None
TLA  A 401 ( 4.7A)
 0.91A 2x9gA-3os7A:
undetectable		 2x9gA-3os7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 VAL A 189
ASN A 289
TRP A 288
 None
None
TLA  A 401 (-4.4A)
 1.10A 2y00B-3os7A:
undetectable		 2y00B-3os7A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		5 / 9 TYR A 106
PHE A  96
PRO A  97
GLY A 109
ILE A 111
 PG4  A 400 ( 4.4A)
PG4  A 400 ( 3.9A)
PG4  A 400 (-4.4A)
None
None
 1.45A 3csjB-3os7A:
undetectable		 3csjB-3os7A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 HIS A 108
GLU A 100
ASN A 216
 TLA  A 401 (-3.9A)
None
None
 1.04A 4bupB-3os7A:
undetectable		 4bupB-3os7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		4 / 7 ASN A 310
PRO A 309
PHE A 320
TYR A 284
 None
PG4  A 400 ( 4.9A)
None
PG4  A 344 (-4.4A)
 1.45A 4v2yC-3os7A:
undetectable		 4v2yC-3os7A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 ASN A 310
PRO A 309
PHE A 320
TYR A 284
 None
PG4  A 400 ( 4.9A)
None
PG4  A 344 (-4.4A)
 1.43A 4v2zC-3os7A:
undetectable		 4v2zC-3os7A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		5 / 9 LEU A  73
VAL A  40
LEU A  52
LEU A  76
PRO A  55
 None
 1.23A 5og9A-3os7A:
undetectable		 5og9A-3os7A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		4 / 8 ASN A 310
PRO A 309
PHE A 320
TYR A 284
 None
PG4  A 400 ( 4.9A)
None
PG4  A 344 (-4.4A)
 1.46A 5oh1C-3os7A:
undetectable		 5oh1C-3os7A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 HIS A 108
ARG A  81
ILE A 107
 TLA  A 401 (-3.9A)
TLA  A 401 ( 4.1A)
None
 0.88A 6fgdA-3os7A:
undetectable		 6fgdA-3os7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3os7 GALACTOSE
MUTAROTASE-LIKE
PROTEIN
(Clostridium
acetobutylicum) 		3 / 3 TRP A  14
ILE A  32
GLU A  41
 None
 0.62A 6hcxA-3os7A:
undetectable		 6hcxA-3os7A:
13.33