SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3osj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 3osj PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 8 ASN A 339
LEU A 376
ALA A 379
LEU A 380
 None
 0.98A 1hwiB-3osjA:
undetectable		 1hwiB-3osjA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 3osj PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 8 ASN A 339
LEU A 376
ALA A 379
LEU A 380
 None
 0.96A 1hwiC-3osjA:
undetectable		 1hwiC-3osjA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3osj PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 7 ASP A 382
VAL A 320
ARG A 321
TYR A 386
 None
 1.10A 2yfbA-3osjA:
undetectable		 2yfbA-3osjA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3osj PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 8 LEU A 373
LEU A 376
VAL A 377
ILE A 350
 None
 0.90A 4oj4A-3osjA:
undetectable		 4oj4A-3osjA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 3osj PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 10 PHE A 390
TYR A 286
THR A 295
PHE A 319
VAL A 320
 None
 1.32A 6hu9C-3osjA:
undetectable		 6hu9C-3osjA:
17.68