SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3osl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 11 LEU A 192
GLY A 196
THR A 199
VAL A 144
VAL A 163
 None
 0.96A 1akdA-3oslA:
undetectable		 1akdA-3oslA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		4 / 7 PHE A 194
LEU A 161
VAL A 144
LEU A 212
 None
 0.94A 1hk3A-3oslA:
undetectable		 1hk3A-3oslA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 11 LEU A 192
GLY A 196
THR A 199
VAL A 144
VAL A 163
 None
 0.89A 2a1nA-3oslA:
undetectable		 2a1nA-3oslA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		4 / 7 SER A 313
SER A 311
PHE A 394
GLU A 385
 None
None
None
ZN  A 999 ( 4.8A)
 1.31A 2c8aA-3oslA:
undetectable		 2c8aA-3oslA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 7 GLY A 393
SER A 313
SER A 311
PHE A 394
GLU A 385
 None
None
None
None
ZN  A 999 ( 4.8A)
 1.34A 2c8aB-3oslA:
undetectable		 2c8aB-3oslA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		4 / 6 SER A 313
SER A 311
PHE A 394
GLU A 385
 None
None
None
ZN  A 999 ( 4.8A)
 1.36A 2c8aC-3oslA:
undetectable		 2c8aC-3oslA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		4 / 5 SER A 311
LEU A 395
GLY A 393
ARG A 236
 None
 0.97A 2j2pA-3oslA:
undetectable
2j2pB-3oslA:
undetectable		 2j2pA-3oslA:
17.90
2j2pB-3oslA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		4 / 6 ARG A 236
SER A 311
LEU A 395
GLY A 393
 None
 1.03A 2j2pD-3oslA:
undetectable
2j2pF-3oslA:
undetectable		 2j2pD-3oslA:
17.90
2j2pF-3oslA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		4 / 6 GLU A 407
MET A 309
PHE A 190
ILE A 186
 None
 1.18A 2w98B-3oslA:
undetectable		 2w98B-3oslA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		3 / 3 GLU A 385
HIS A 181
GLU A 184
 ZN  A 999 ( 4.8A)
ZN  A 999 (-3.1A)
ZN  A 999 (-2.1A)
 0.80A 2x45B-3oslA:
undetectable		 2x45B-3oslA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		3 / 3 GLU A 385
HIS A 181
GLU A 184
 ZN  A 999 ( 4.8A)
ZN  A 999 (-3.1A)
ZN  A 999 (-2.1A)
 0.82A 2x45C-3oslA:
undetectable		 2x45C-3oslA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		4 / 8 THR A 354
GLN A 314
TYR A 312
SER A 361
 None
 1.22A 2xz5C-3oslA:
undetectable
2xz5D-3oslA:
undetectable		 2xz5C-3oslA:
18.72
2xz5D-3oslA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 10 GLY A 368
PHE A 259
HIS A 181
THR A 383
ILE A 180
 None
None
ZN  A 999 (-3.1A)
None
None
 1.09A 2y7wB-3oslA:
undetectable		 2y7wB-3oslA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 12 ILE A 277
ASN A 256
GLY A 368
ASP A 370
LEU A 364
 None
 1.25A 2zw9A-3oslA:
undetectable		 2zw9A-3oslA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 12 ILE A 303
LEU A 296
ASN A 256
ILE A 176
VAL A 419
 None
 1.14A 3a51C-3oslA:
undetectable		 3a51C-3oslA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 12 ARG A 324
ASP A 371
SER A 369
GLU A 267
ALA A 365
 None
 1.27A 3t7sA-3oslA:
undetectable		 3t7sA-3oslA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 12 ARG A 324
ASP A 371
SER A 369
GLU A 267
ALA A 365
 None
 1.26A 3t7sB-3oslA:
undetectable		 3t7sB-3oslA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 12 ARG A 324
ASP A 371
SER A 369
GLU A 267
ALA A 365
 None
 1.25A 3t7sD-3oslA:
undetectable		 3t7sD-3oslA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		4 / 7 GLY A 368
ASN A 256
GLY A 280
THR A 281
 None
 0.83A 3tajA-3oslA:
undetectable		 3tajA-3oslA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		3 / 3 TRP A 185
VAL A 225
TRP A 232
 None
 1.15A 3zq8A-3oslA:
undetectable
3zq8B-3oslA:
undetectable		 3zq8A-3oslA:
3.42
3zq8B-3oslA:
3.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 12 ILE A 133
GLY A 196
THR A 199
VAL A 144
VAL A 163
 None
 1.04A 4c9lA-3oslA:
undetectable		 4c9lA-3oslA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		6 / 12 ILE A 133
LEU A 192
GLY A 196
THR A 199
VAL A 144
VAL A 163
 None
 1.38A 4c9oA-3oslA:
undetectable		 4c9oA-3oslA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		6 / 12 ILE A 133
LEU A 192
GLY A 196
THR A 199
VAL A 144
VAL A 163
 None
 1.38A 4c9oB-3oslA:
undetectable		 4c9oB-3oslA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JDC_D_6JPD302_1
(PTERIDINE REDUCTASE)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 11 HIS A 181
ARG A 297
ASP A 177
TYR A 306
VAL A 289
 ZN  A 999 (-3.1A)
None
None
None
None
 1.44A 5jdcA-3oslA:
undetectable
5jdcD-3oslA:
undetectable		 5jdcA-3oslA:
19.80
5jdcD-3oslA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 12 LEU A 212
ILE A 219
PHE A 217
ILE A 415
ALA A 411
 None
 1.15A 5vc0A-3oslA:
undetectable		 5vc0A-3oslA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 3osl CARBOXYPEPTIDASE B2
(Bos
taurus) 		5 / 12 MET A 215
ALA A 413
VAL A 336
ASP A 370
PHE A 382
 None
 1.29A 5vlmD-3oslA:
undetectable		 5vlmD-3oslA:
19.44