SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3osr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 10 GLU A 130
GLU A 131
LEU A 135
MET A 224
LEU A 115
 None
 1.48A 1a29A-3osrA:
0.4		 1a29A-3osrA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 6 VAL A   8
VAL A  50
ILE A  60
ASN A 267
 None
 0.94A 1e06A-3osrA:
undetectable		 1e06A-3osrA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 10 HIS A 348
LEU A 465
LEU A 476
THR A 474
THR A 475
 None
None
C12  A 478 ( 4.2A)
C12  A 478 ( 4.7A)
None
 1.40A 1rj6A-3osrA:
undetectable		 1rj6A-3osrA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 10 HIS A 348
LEU A 465
LEU A 476
THR A 474
THR A 475
 None
None
C12  A 478 ( 4.2A)
C12  A 478 ( 4.7A)
None
 1.37A 1rj6B-3osrA:
undetectable		 1rj6B-3osrA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 8 ILE A 510
ASP A 541
GLY A 516
PHE A 512
 None
 0.82A 1rtsA-3osrA:
undetectable		 1rtsA-3osrA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 7 ILE A 510
ASP A 541
GLY A 516
PHE A 512
 None
 0.82A 1rtsB-3osrA:
undetectable		 1rtsB-3osrA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 7 ALA A 522
TYR A 504
ILE A 505
ILE A 355
 None
 0.92A 1upfB-3osrA:
undetectable		 1upfB-3osrA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		5 / 10 LEU A 192
LEU A 195
ILE A 161
GLU A 153
LEU A 151
 None
None
None
MAL  A 700 (-3.6A)
None
 1.24A 1wopA-3osrA:
undetectable		 1wopA-3osrA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 5 LEU A 262
GLY A 289
ALA A 109
ILE A 108
 None
 0.81A 2aohB-3osrA:
undetectable		 2aohB-3osrA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		5 / 9 THR A  93
LEU A  89
GLU A 309
LEU A 299
GLU A 291
 None
 1.47A 2azqA-3osrA:
undetectable		 2azqA-3osrA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 11 ALA A 303
ILE A 108
VAL A  97
LEU A  76
ILE A  79
 None
 1.25A 2h42A-3osrA:
undetectable		 2h42A-3osrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		3 / 3 ASN A 337
LEU A 553
HIS A 336
 None
 0.82A 2q6fB-3osrA:
undetectable		 2q6fB-3osrA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 7 VAL A  97
ALA A 105
PHE A  92
PRO A  91
 None
 1.03A 2q6oA-3osrA:
2.1		 2q6oA-3osrA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 LEU A 456
LEU A 454
ILE A 426
ALA A 449
PHE A 483
 C12  A 478 ( 4.6A)
C12  A 478 ( 4.8A)
None
None
None
 1.13A 2qb4A-3osrA:
undetectable		 2qb4A-3osrA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 LEU A 192
THR A 193
ALA A 595
THR A 594
ILE A 597
 None
 1.23A 3a35A-3osrA:
undetectable		 3a35A-3osrA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 7 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.70A 3bjwC-3osrA:
undetectable		 3bjwC-3osrA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 8 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.89A 3bjwA-3osrA:
undetectable		 3bjwA-3osrA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 6 PRO A 126
LEU A 147
ALA A 223
PRO A 125
 None
 1.34A 3gv1A-3osrA:
undetectable
3gv1C-3osrA:
undetectable		 3gv1A-3osrA:
11.45
3gv1C-3osrA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 6 LEU A 147
ALA A 223
PRO A 125
PRO A 126
 None
 1.33A 3gv1A-3osrA:
undetectable
3gv1B-3osrA:
undetectable		 3gv1A-3osrA:
11.45
3gv1B-3osrA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 VAL A 592
GLY A 187
ALA A 188
LEU A 192
LEU A 160
 None
 1.05A 3hs6A-3osrA:
undetectable		 3hs6A-3osrA:
22.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		10 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
GLU A 111
PRO A 154
TRP A 230
 MAL  A 700 (-3.1A)
MAL  A 700 (-2.8A)
None
None
None
MAL  A 700 (-3.3A)
MAL  A 700 (-2.8A)
MAL  A 700 (-3.0A)
MAL  A 700 (-3.6A)
MAL  A 700 ( 4.4A)
 0.37A 3jyrA-3osrA:
63.0		 3jyrA-3osrA:
53.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		6 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 579
TRP A 589
 MAL  A 700 ( 4.7A)
MAL  A 700 (-4.4A)
MAL  A 700 (-3.6A)
MAL  A 700 (-3.9A)
MAL  A 700 ( 4.1A)
MAL  A 700 (-3.6A)
 0.38A 3jyrA-3osrA:
63.0		 3jyrA-3osrA:
53.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 11 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.16A 3mg0H-3osrA:
undetectable
3mg0I-3osrA:
undetectable		 3mg0H-3osrA:
16.52
3mg0I-3osrA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 VAL A 196
LEU A 160
GLY A 187
ALA A 188
LEU A 610
 None
 0.97A 3n8yB-3osrA:
undetectable		 3n8yB-3osrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 6 ILE A 355
PHE A 495
ALA A 499
ASN A 352
 None
 1.14A 3pgyA-3osrA:
undetectable
3pgyB-3osrA:
undetectable		 3pgyA-3osrA:
21.25
3pgyB-3osrA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 9 PHE A 483
VAL A 524
ASN A 533
ILE A 426
PHE A 420
 None
C12  A 478 ( 4.9A)
C12  A 478 ( 3.5A)
None
None
 1.18A 3t3rB-3osrA:
undetectable		 3t3rB-3osrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 9 PHE A 483
VAL A 524
ASN A 533
ILE A 426
PHE A 420
 None
C12  A 478 ( 4.9A)
C12  A 478 ( 3.5A)
None
None
 1.22A 3t3rC-3osrA:
undetectable		 3t3rC-3osrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 10 PHE A 483
VAL A 524
ASN A 533
ILE A 426
PHE A 420
 None
C12  A 478 ( 4.9A)
C12  A 478 ( 3.5A)
None
None
 1.16A 3t3rD-3osrA:
undetectable		 3t3rD-3osrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 MAL  A 700 (-4.9A)
None
None
MAL  A 700 (-3.0A)
None
 0.86A 3tbgB-3osrA:
undetectable		 3tbgB-3osrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 MAL  A 700 (-4.9A)
None
None
MAL  A 700 (-3.0A)
None
 0.84A 3tbgD-3osrA:
undetectable		 3tbgD-3osrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 ALA A 231
TYR A  17
TYR A 210
ASN A 234
GLY A 228
 None
 1.35A 3vwqA-3osrA:
undetectable		 3vwqA-3osrA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 6 GLU A 308
ASP A 563
ASP A 287
ASN A 294
 None
 1.33A 3vywA-3osrA:
undetectable		 3vywA-3osrA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 7 ASP A 431
THR A 520
SER A 440
PHE A 439
 None
 1.04A 4ac9C-3osrA:
undetectable		 4ac9C-3osrA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 7 ILE A 510
ASP A 541
GLY A 516
PHE A 512
 None
 0.88A 4iqqA-3osrA:
undetectable		 4iqqA-3osrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		3 / 3 VAL A 434
GLY A 436
LYS A 438
 None
 0.73A 4k50A-3osrA:
undetectable		 4k50A-3osrA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		3 / 3 VAL A 434
GLY A 436
LYS A 438
 None
 0.70A 4k50E-3osrA:
undetectable		 4k50E-3osrA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		3 / 3 VAL A 434
GLY A 436
LYS A 438
 None
 0.73A 4k50I-3osrA:
undetectable		 4k50I-3osrA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 ILE A 266
ALA A 105
LEU A  20
VAL A  23
ILE A  59
 None
 1.10A 4m2xG-3osrA:
undetectable		 4m2xG-3osrA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MAL  A 700 (-3.1A)
 0.99A 4n48A-3osrA:
undetectable		 4n48A-3osrA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 6 VAL A 467
LEU A 465
LEU A 537
PHE A 332
 None
None
None
C12  A 478 ( 4.5A)
 0.92A 4o1zA-3osrA:
undetectable		 4o1zA-3osrA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		3 / 3 TYR A 347
ARG A 335
LYS A 333
 None
 0.97A 4wq5B-3osrA:
undetectable		 4wq5B-3osrA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 7 ILE A 510
ASP A 541
GLY A 516
PHE A 512
 None
 0.85A 5h3aA-3osrA:
undetectable		 5h3aA-3osrA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.20A 5l66H-3osrA:
undetectable
5l66I-3osrA:
undetectable		 5l66H-3osrA:
16.82
5l66I-3osrA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 12 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.20A 5l66V-3osrA:
undetectable
5l66W-3osrA:
undetectable		 5l66V-3osrA:
16.82
5l66W-3osrA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		6 / 12 ALA A 591
ALA A 587
GLY A 166
ALA A 188
PHE A 169
VAL A 181
 None
 1.37A 5w4zA-3osrA:
undetectable		 5w4zA-3osrA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		6 / 12 ALA A 591
ALA A 587
GLY A 166
ALA A 188
PHE A 169
VAL A 181
 None
 1.39A 5w4zB-3osrA:
undetectable		 5w4zB-3osrA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 7 ILE A 510
ASP A 541
GLY A 516
PHE A 512
 None
 0.89A 5x5qC-3osrA:
undetectable		 5x5qC-3osrA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		4 / 8 ILE A 510
ASP A 541
GLY A 516
PHE A 512
 None
 0.89A 5x5qF-3osrA:
undetectable		 5x5qF-3osrA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MAL  A 700 (-3.9A)
None
None
 0.81A 6b58A-3osrA:
undetectable		 6b58A-3osrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		4 / 8 ILE A 548
GLN A 344
THR A 509
TYR A 349
 None
 0.87A 6cduD-3osrA:
undetectable
6cduE-3osrA:
undetectable		 6cduD-3osrA:
19.61
6cduE-3osrA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		5 / 10 SER A 498
LEU A 368
SER A 484
ILE A 319
PRO A 363
 None
 1.48A 6dlzB-3osrA:
5.9
6dlzC-3osrA:
5.8		 6dlzB-3osrA:
7.63
6dlzC-3osrA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		5 / 10 SER A 498
LEU A 368
SER A 484
ILE A 319
PRO A 363
 None
 1.47A 6dm1B-3osrA:
5.6
6dm1C-3osrA:
5.9		 6dm1B-3osrA:
7.63
6dm1C-3osrA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		5 / 10 SER A 498
LEU A 368
SER A 484
ILE A 319
PRO A 363
 None
 1.47A 6dm2B-3osrA:
5.9
6dm2C-3osrA:
4.7		 6dm2B-3osrA:
7.63
6dm2C-3osrA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		5 / 10 ILE A 319
PRO A 363
SER A 498
LEU A 368
SER A 484
 None
 1.47A 6dm2A-3osrA:
4.6
6dm2D-3osrA:
6.7		 6dm2A-3osrA:
7.63
6dm2D-3osrA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3osr MALTOSE-BINDING
PERIPLASMIC
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Escherichia
coli;
Aequorea
victoria) 		5 / 12 LEU A 275
GLY A  24
VAL A  35
LEU A   7
ILE A   9
 None
 0.93A 6ecxA-3osrA:
undetectable		 6ecxA-3osrA:
17.68