SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ot2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WYG_A_SALA4005_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	3ot2	UNCHARACTERIZED PROTEIN (Trichormus variabilis)	5 / 10	GLU A 67 ARG A 69 THR A 77 ALA A 23 GLU A 19	None BU1 A 189 ( 4.2A) None EDO A 197 (-3.5A) EDO A 197 ( 3.2A)	1.44A	1wygA-3ot2A: undetectable	1wygA-3ot2A: 9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DH0_A_SAMA220_1 (SAM DEPENDENT METHYLTRANSFERASE)	3ot2	UNCHARACTERIZED PROTEIN (Trichormus variabilis)	4 / 8	LYS A 34 GLN A 116 GLU A 67 GLU A 25	None	1.17A	3dh0A-3ot2A: undetectable	3dh0A-3ot2A: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DX7_B_DM2B1104_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	3ot2	UNCHARACTERIZED PROTEIN (Trichormus variabilis)	4 / 8	GLN A 134 PHE A 65 ILE A 81 VAL A 49	None	0.95A	4dx7B-3ot2A: undetectable	4dx7B-3ot2A: 10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HGC_A_HCYA501_1 (SERPIN)	3ot2	UNCHARACTERIZED PROTEIN (Trichormus variabilis)	5 / 12	ARG A 69 PHE A 14 ILE A 31 GLN A 33 SER A 24	BU1 A 189 ( 4.2A) BU1 A 189 (-4.0A) None None BU1 A 189 ( 4.2A)	1.33A	5hgcA-3ot2A: undetectable	5hgcA-3ot2A: 20.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WYG_A_SALA4005_1","XANTHINE DEHYDROGENASE\/OXIDASE","3ot2","UNCHARACTERIZED PROTEIN","Trichormus variabilis",5,"GLU A  67;ARG A  69;THR A  77;ALA A  23;GLU A  19","None;BU1 A 189 ( 4.2A);None;EDO A 197 (-3.5A);EDO A 197 ( 3.2A)","1.44A","1wygA-3ot2A:undetectable","1wygA-3ot2A:9.47"],["3DH0_A_SAMA220_1","SAM DEPENDENT METHYLTRANSFERASE","3ot2","UNCHARACTERIZED PROTEIN","Trichormus variabilis",4,"LYS A  34;GLN A 116;GLU A  67;GLU A  25","None","1.17A","3dh0A-3ot2A:undetectable","3dh0A-3ot2A:23.42"],["4DX7_B_DM2B1104_1","ACRIFLAVINE RESISTANCE PROTEIN B","3ot2","UNCHARACTERIZED PROTEIN","Trichormus variabilis",4,"GLN A 134;PHE A  65;ILE A  81;VAL A  49","None","0.95A","4dx7B-3ot2A:undetectable","4dx7B-3ot2A:10.76"],["5HGC_A_HCYA501_1","SERPIN","3ot2","UNCHARACTERIZED PROTEIN","Trichormus variabilis",5,"ARG A  69;PHE A  14;ILE A  31;GLN A  33;SER A  24","BU1 A 189 ( 4.2A);BU1 A 189 (-4.0A);None;None;BU1 A 189 ( 4.2A)","1.33A","5hgcA-3ot2A:undetectable","5hgcA-3ot2A:20.05"]]