SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ot4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 3ot4 PUTATIVE
ISOCHORISMATASE
(Bordetella
bronchiseptica) 		4 / 4 GLY A  43
ASP A 174
GLY A 144
THR A  51
 None
 0.97A 1hxbB-3ot4A:
undetectable		 1hxbB-3ot4A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3ot4 PUTATIVE
ISOCHORISMATASE
(Bordetella
bronchiseptica) 		3 / 3 SER A  69
VAL A 142
LEU A  26
 None
 0.74A 1yajG-3ot4A:
undetectable		 1yajG-3ot4A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3ot4 PUTATIVE
ISOCHORISMATASE
(Bordetella
bronchiseptica) 		5 / 10 ALA A  16
ALA A 193
LEU A 166
LEU A  19
GLU A 199
 None
 1.24A 2bxeA-3ot4A:
undetectable		 2bxeA-3ot4A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 3ot4 PUTATIVE
ISOCHORISMATASE
(Bordetella
bronchiseptica) 		4 / 4 GLY A  43
ASP A 174
GLY A 144
THR A  51
 None
 0.89A 3k4vC-3ot4A:
undetectable		 3k4vC-3ot4A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3ot4 PUTATIVE
ISOCHORISMATASE
(Bordetella
bronchiseptica) 		4 / 8 ALA A  48
THR A  52
VAL A 151
VAL A 167
 None
None
CSO  A 150 ( 3.4A)
None
 0.82A 3me6B-3ot4A:
undetectable		 3me6B-3ot4A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3ot4 PUTATIVE
ISOCHORISMATASE
(Bordetella
bronchiseptica) 		4 / 8 ALA A 153
THR A 126
VAL A 115
SER A  69
 CSO  A 150 ( 3.7A)
None
None
None
 0.77A 4r20A-3ot4A:
undetectable		 4r20A-3ot4A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3ot4 PUTATIVE
ISOCHORISMATASE
(Bordetella
bronchiseptica) 		5 / 12 SER A 154
SER A  84
PHE A  40
THR A 126
GLY A 125
 CSO  A 150 ( 2.6A)
None
None
None
None
 1.28A 4zjlA-3ot4A:
undetectable		 4zjlA-3ot4A:
13.41