SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ot5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 1gtnB-3ot5A:
undetectable
1gtnC-3ot5A:
undetectable
1gtnB-3ot5A:
13.22
1gtnC-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.10A 1gtnH-3ot5A:
undetectable
1gtnI-3ot5A:
undetectable
1gtnH-3ot5A:
13.22
1gtnI-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 11 GLY A  11
ALA A 106
THR A  40
ILE A   9
ALA A 105
None
1.12A 1gtnM-3ot5A:
undetectable
1gtnN-3ot5A:
undetectable
1gtnM-3ot5A:
13.22
1gtnN-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 9 ALA A 105
THR A 100
THR A  40
SER A 103
ALA A 106
None
1.37A 1gtnQ-3ot5A:
undetectable
1gtnR-3ot5A:
undetectable
1gtnQ-3ot5A:
13.22
1gtnR-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 11 LEU A  22
ALA A  25
ALA A 356
THR A 176
VAL A 120
None
1.10A 1ictA-3ot5A:
undetectable
1ictC-3ot5A:
undetectable
1ictA-3ot5A:
17.09
1ictC-3ot5A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 11 THR A 153
GLY A 123
GLU A 121
GLU A 290
ASN A 159
None
1.35A 1odiA-3ot5A:
3.2
1odiA-3ot5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 GLY A  11
ALA A 106
THR A  40
ILE A   9
ALA A 105
None
1.13A 1utdT-3ot5A:
undetectable
1utdU-3ot5A:
undetectable
1utdT-3ot5A:
13.22
1utdU-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 PHE A 377
ASP A 376
ARG A 373
LEU A  95
ILE A 148
None
1.46A 1ynnC-3ot5A:
0.0
1ynnC-3ot5A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 ILE A   4
ALA A  25
LEU A  26
LEU A  95
PHE A 368
None
1.16A 2h77A-3ot5A:
undetectable
2h77A-3ot5A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 6 PRO A 298
LEU A 300
LYS A 318
GLY A 311
None
0.93A 2hs2B-3ot5A:
undetectable
2hs2B-3ot5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 4 LEU A 117
ILE A   9
ILE A  82
ALA A 109
None
0.88A 2i30A-3ot5A:
undetectable
2i30A-3ot5A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 4 VAL A 301
THR A 283
VAL A 288
GLY A 287
None
1.16A 2p2fB-3ot5A:
5.2
2p2fB-3ot5A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 THR A  36
ILE A   9
ILE A  86
ALA A 109
LEU A 117
None
1.07A 3a50A-3ot5A:
undetectable
3a50A-3ot5A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 THR A  36
ILE A   9
ILE A  86
ALA A 109
LEU A 117
None
1.09A 3a51E-3ot5A:
undetectable
3a51E-3ot5A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 GLY A 286
ALA A 268
LEU A 275
LEU A 204
VAL A 281
None
0.91A 3adxB-3ot5A:
undetectable
3adxB-3ot5A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
3 / 3 GLY A  98
PRO A 152
LEU A 124
None
0.51A 3hcpB-3ot5A:
3.7
3hcpB-3ot5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 6 PRO A 293
GLY A 294
LEU A 181
GLU A 290
None
PGE  A 381 (-4.8A)
PGE  A 381 ( 4.6A)
None
0.97A 3zqtA-3ot5A:
0.9
3zqtA-3ot5A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1103_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 5 ASN A 337
ARG A 231
HIS A 341
LEU A 280
None
0.98A 4g5jA-3ot5A:
undetectable
4g5jA-3ot5A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 ILE A   4
ALA A  25
LEU A  26
LEU A  95
PHE A 368
None
1.10A 4lnwA-3ot5A:
undetectable
4lnwA-3ot5A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 ILE A   4
ALA A  25
LEU A  26
LEU A  95
PHE A 368
None
1.12A 4lnxA-3ot5A:
undetectable
4lnxA-3ot5A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 9 THR A 316
GLY A 315
LEU A 317
PRO A 350
VAL A 301
None
1.36A 4mjrA-3ot5A:
undetectable
4mjrA-3ot5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 6 GLU A 310
THR A 176
HIS A  97
LEU A 124
None
1.00A 4pgfA-3ot5A:
3.2
4pgfA-3ot5A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 8 LEU A 204
VAL A 297
VAL A 288
LEU A 202
None
1.05A 4q0bA-3ot5A:
undetectable
4q0bA-3ot5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 5eeuF-3ot5A:
undetectable
5eeuG-3ot5A:
undetectable
5eeuF-3ot5A:
13.22
5eeuG-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.03A 5eeuI-3ot5A:
undetectable
5eeuJ-3ot5A:
undetectable
5eeuI-3ot5A:
13.22
5eeuJ-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 GLY A  11
ALA A 106
THR A  40
ILE A   9
ALA A 105
None
1.08A 5eeuO-3ot5A:
undetectable
5eeuP-3ot5A:
undetectable
5eeuO-3ot5A:
13.22
5eeuP-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 GLY A  11
ALA A 106
THR A  40
ILE A   9
ALA A 105
None
1.09A 5eeuQ-3ot5A:
undetectable
5eeuR-3ot5A:
undetectable
5eeuQ-3ot5A:
13.22
5eeuR-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 5eevF-3ot5A:
undetectable
5eevG-3ot5A:
undetectable
5eevF-3ot5A:
13.22
5eevG-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.03A 5eevI-3ot5A:
undetectable
5eevJ-3ot5A:
undetectable
5eevI-3ot5A:
13.22
5eevJ-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 GLY A  11
ALA A 106
THR A  40
ILE A   9
ALA A 105
None
1.09A 5eevQ-3ot5A:
undetectable
5eevR-3ot5A:
undetectable
5eevQ-3ot5A:
13.22
5eevR-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 5eewF-3ot5A:
undetectable
5eewG-3ot5A:
undetectable
5eewF-3ot5A:
13.22
5eewG-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.03A 5eewI-3ot5A:
undetectable
5eewJ-3ot5A:
undetectable
5eewI-3ot5A:
13.22
5eewJ-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 GLY A  11
ALA A 106
THR A  40
ILE A   9
ALA A 105
None
1.09A 5eewQ-3ot5A:
undetectable
5eewR-3ot5A:
undetectable
5eewQ-3ot5A:
13.22
5eewR-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 5eexF-3ot5A:
undetectable
5eexG-3ot5A:
undetectable
5eexF-3ot5A:
13.22
5eexG-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 5eeyF-3ot5A:
undetectable
5eeyG-3ot5A:
undetectable
5eeyF-3ot5A:
13.22
5eeyG-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 5eezF-3ot5A:
undetectable
5eezG-3ot5A:
undetectable
5eezF-3ot5A:
13.22
5eezG-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 5ef0F-3ot5A:
undetectable
5ef0G-3ot5A:
undetectable
5ef0F-3ot5A:
13.22
5ef0G-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.06A 5ef1F-3ot5A:
undetectable
5ef1G-3ot5A:
undetectable
5ef1F-3ot5A:
13.22
5ef1G-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.07A 5ef2F-3ot5A:
undetectable
5ef2G-3ot5A:
undetectable
5ef2F-3ot5A:
13.22
5ef2G-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 10 ALA A 105
GLY A  11
ALA A 106
THR A  40
ILE A   9
None
1.07A 5ef3F-3ot5A:
undetectable
5ef3G-3ot5A:
undetectable
5ef3F-3ot5A:
13.22
5ef3G-3ot5A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
3 / 3 ALA A 156
ASN A 159
LEU A 160
None
0.40A 5i1nB-3ot5A:
undetectable
5i1nB-3ot5A:
5.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
3 / 3 ALA A 156
ASN A 159
LEU A 160
None
0.45A 5i1oA-3ot5A:
undetectable
5i1oA-3ot5A:
5.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 7 LEU A 194
TYR A 189
THR A 184
LEU A 202
None
1.03A 5jq7B-3ot5A:
undetectable
5jq7B-3ot5A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 11 THR A 206
ALA A 207
VAL A 299
GLY A 287
GLY A 286
None
0.87A 5lf7K-3ot5A:
undetectable
5lf7L-3ot5A:
undetectable
5lf7K-3ot5A:
20.82
5lf7L-3ot5A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 11 THR A 206
ALA A 207
VAL A 299
GLY A 287
GLY A 286
None
0.86A 5lf7Y-3ot5A:
undetectable
5lf7Z-3ot5A:
undetectable
5lf7Y-3ot5A:
20.82
5lf7Z-3ot5A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
4 / 8 ILE A 364
THR A 176
GLU A 121
SER A 151
None
1.06A 6fbvC-3ot5A:
undetectable
6fbvC-3ot5A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes)
5 / 12 VAL A  78
ILE A  82
MET A 145
VAL A  96
ILE A   9
None
1.07A 6gsdA-3ot5A:
8.4
6gsdA-3ot5A:
10.92