SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3otl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 3otl PUTATIVE
UNCHARACTERIZED
PROTEIN
(Rhizobium
leguminosarum) 		4 / 6 TYR A  90
TYR A  73
GLU A 121
VAL A 106
 None
MES  A 159 ( 4.9A)
None
None
 0.91A 1q13A-3otlA:
undetectable		 1q13A-3otlA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 3otl PUTATIVE
UNCHARACTERIZED
PROTEIN
(Rhizobium
leguminosarum) 		5 / 12 MET A 117
ILE A  86
TYR A  88
VAL A 106
PHE A  53
 None
 1.29A 3a8iB-3otlA:
undetectable		 3a8iB-3otlA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 3otl PUTATIVE
UNCHARACTERIZED
PROTEIN
(Rhizobium
leguminosarum) 		5 / 12 MET A 117
ILE A  86
TYR A  88
VAL A 106
PHE A  53
 None
 1.30A 3a8iC-3otlA:
undetectable		 3a8iC-3otlA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 3otl PUTATIVE
UNCHARACTERIZED
PROTEIN
(Rhizobium
leguminosarum) 		5 / 12 MET A 117
ILE A  86
TYR A  88
VAL A 106
PHE A  53
 None
 1.25A 3a8iD-3otlA:
undetectable		 3a8iD-3otlA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3otl PUTATIVE
UNCHARACTERIZED
PROTEIN
(Rhizobium
leguminosarum) 		4 / 7 THR A 105
VAL A 118
THR A 120
VAL A  12
 None
 0.27A 3em0B-3otlA:
3.3		 3em0B-3otlA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3otl PUTATIVE
UNCHARACTERIZED
PROTEIN
(Rhizobium
leguminosarum) 		5 / 12 PHE A  25
LEU A 143
PHE A 108
MET A 117
TYR A  77
 None
 1.16A 4xldA-3otlA:
undetectable		 4xldA-3otlA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3otl PUTATIVE
UNCHARACTERIZED
PROTEIN
(Rhizobium
leguminosarum) 		4 / 6 ARG A 135
THR A 104
GLU A 121
SER A 102
 MES  A 159 (-3.8A)
None
None
None
 1.01A 5ny7A-3otlA:
undetectable		 5ny7A-3otlA:
21.55