SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 5 THR A 325
ASP A 315
HIS A 313
HIS A 374
 None
FE2  A   1 ( 2.5A)
FE2  A   1 ( 3.3A)
FE2  A   1 ( 3.2A)
 1.22A 1ei6A-3ouiA:
undetectable		 1ei6A-3ouiA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 5 ARG A 383
MET A 299
ASN A 316
TYR A 303
 42Z  A 393 (-2.9A)
42Z  A 393 (-3.3A)
None
None
 1.30A 1nbiA-3ouiA:
0.0		 1nbiA-3ouiA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 5 ARG A 383
MET A 299
ASN A 316
TYR A 303
 42Z  A 393 (-2.9A)
42Z  A 393 (-3.3A)
None
None
 1.31A 1nbiB-3ouiA:
0.0		 1nbiB-3ouiA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 7 ARG A 383
ALA A 385
TYR A 303
ILE A 256
 42Z  A 393 (-2.9A)
42Z  A 393 ( 4.3A)
None
None
 1.02A 1oniA-3ouiA:
undetectable
1oniB-3ouiA:
undetectable		 1oniA-3ouiA:
21.23
1oniB-3ouiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 6 PHE A 360
ASN A 331
ILE A 222
GLY A 223
 None
 0.95A 1oniA-3ouiA:
undetectable
1oniB-3ouiA:
undetectable		 1oniA-3ouiA:
21.23
1oniB-3ouiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 6 ARG A 383
ALA A 385
TYR A 303
ILE A 256
 42Z  A 393 (-2.9A)
42Z  A 393 ( 4.3A)
None
None
 0.96A 1oniB-3ouiA:
undetectable
1oniC-3ouiA:
undetectable		 1oniB-3ouiA:
21.23
1oniC-3ouiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 6 PHE A 360
ASN A 331
ILE A 222
GLY A 223
 None
 0.91A 1oniD-3ouiA:
undetectable
1oniF-3ouiA:
undetectable		 1oniD-3ouiA:
21.23
1oniF-3ouiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 6 ARG A 383
ALA A 385
TYR A 303
ILE A 256
 42Z  A 393 (-2.9A)
42Z  A 393 ( 4.3A)
None
None
 1.03A 1oniH-3ouiA:
undetectable
1oniI-3ouiA:
undetectable		 1oniH-3ouiA:
21.23
1oniI-3ouiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 7 TYR A 303
ILE A 256
ARG A 383
ALA A 385
 None
None
42Z  A 393 (-2.9A)
42Z  A 393 ( 4.3A)
 0.94A 1oniG-3ouiA:
undetectable
1oniI-3ouiA:
undetectable		 1oniG-3ouiA:
21.23
1oniI-3ouiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 7 ILE A 222
GLY A 223
PHE A 360
ASN A 331
 None
 0.70A 1oniG-3ouiA:
undetectable
1oniI-3ouiA:
undetectable		 1oniG-3ouiA:
21.23
1oniI-3ouiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOF_A_PNNA1312_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		5 / 11 HIS A 313
ASP A 315
THR A 325
HIS A 374
VAL A 376
 FE2  A   1 ( 3.3A)
FE2  A   1 ( 2.5A)
None
FE2  A   1 ( 3.2A)
42Z  A 393 (-4.9A)
 0.61A 1uofA-3ouiA:
4.4		 1uofA-3ouiA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_1
(HYPOTHETICAL PROTEIN
PH0226)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 4 TYR A 303
ARG A 383
ASP A 315
ASP A 369
 None
42Z  A 393 (-2.9A)
FE2  A   1 ( 2.5A)
None
 1.29A 1ve3A-3ouiA:
0.8		 1ve3A-3ouiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_1
(HYPOTHETICAL PROTEIN
PH0226)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 4 TYR A 303
ARG A 383
ASP A 315
ASP A 369
 None
42Z  A 393 (-2.9A)
FE2  A   1 ( 2.5A)
None
 1.31A 1ve3B-3ouiA:
0.0		 1ve3B-3ouiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		3 / 3 ARG A 312
PHE A 346
PRO A 347
 None
 0.79A 3zoaB-3ouiA:
3.0		 3zoaB-3ouiA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 3oui EGL NINE HOMOLOG 1
(Homo
sapiens) 		4 / 6 TYR A 303
HIS A 313
HIS A 374
TYR A 329
 None
FE2  A   1 ( 3.3A)
FE2  A   1 ( 3.2A)
42Z  A 393 (-4.5A)
 1.40A 4df2A-3ouiA:
undetectable		 4df2A-3ouiA:
20.16