SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oum'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		3 / 3 ASP A 177
ARG A 117
ILE A 115
 None
 0.69A 1a4gB-3oumA:
undetectable		 1a4gB-3oumA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		3 / 3 SER A 116
GLU A  72
ASP A 125
 None
 0.81A 2avdB-3oumA:
undetectable		 2avdB-3oumA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		5 / 12 TYR A  21
ILE A 139
ILE A   4
ILE A  46
TYR A  59
 None
 0.94A 2efjA-3oumA:
undetectable		 2efjA-3oumA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		6 / 12 LEU A   7
GLY A 137
ASP A 177
GLY A 174
ILE A 173
ILE A   4
 None
 1.47A 2nmzA-3oumA:
undetectable		 2nmzA-3oumA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		5 / 12 ILE A  61
ILE A 112
ASP A 106
PHE A  37
ALA A  36
 None
 1.39A 2qmjA-3oumA:
undetectable		 2qmjA-3oumA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		4 / 7 GLU A 138
GLU A 113
ARG A 117
SER A 101
 MN  A 233 (-2.8A)
MN  A 233 ( 2.5A)
None
None
 1.15A 2zt7A-3oumA:
undetectable		 2zt7A-3oumA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		5 / 10 ILE A 136
ILE A  46
PHE A  20
PRO A 107
LEU A 133
 None
 1.12A 3elzB-3oumA:
undetectable		 3elzB-3oumA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		5 / 12 LEU A  25
GLY A  73
ILE A 115
LEU A  41
ILE A 136
 None
 1.00A 3ijdB-3oumA:
undetectable		 3ijdB-3oumA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		6 / 12 LEU A   7
GLY A 137
ASP A 177
GLY A 174
ILE A 173
ILE A   4
 None
 1.45A 3jw2A-3oumA:
undetectable		 3jw2A-3oumA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		6 / 12 LEU A   7
GLY A 137
ASP A 177
GLY A 174
ILE A 173
ILE A   4
 None
 1.47A 3s54B-3oumA:
undetectable		 3s54B-3oumA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		5 / 11 SER A 108
GLY A 109
ILE A  46
HIS A  60
ILE A  61
 None
None
None
MN  A 233 ( 3.5A)
None
 0.99A 4dt8A-3oumA:
undetectable		 4dt8A-3oumA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		4 / 5 ARG A 187
GLY A 169
ALA A 168
GLY A 183
 None
 0.86A 4u9uA-3oumA:
undetectable		 4u9uA-3oumA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		4 / 5 ARG A 187
GLY A 169
ALA A 168
GLY A 183
 None
 0.79A 4u9uB-3oumA:
undetectable		 4u9uB-3oumA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3oum TOXOFLAVIN-DEGRADING
ENZYME
(Paenibacillus
polymyxa) 		4 / 6 ILE A  63
LEU A 114
TYR A  21
MET A  24
 None
 1.07A 6nmfN-3oumA:
undetectable
6nmfW-3oumA:
undetectable		 6nmfN-3oumA:
18.22
6nmfW-3oumA:
12.55