SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 5 LEU A  22
TYR A  32
ARG A  35
THR A  21
 None
 1.38A 1nw3A-3ounA:
undetectable		 1nw3A-3ounA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 8 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.91A 1v54C-3ounA:
undetectable
1v54J-3ounA:
undetectable		 1v54C-3ounA:
19.85
1v54J-3ounA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  61
LEU A  71
LEU A  93
LEU A  34
 None
 1.03A 2ab2A-3ounA:
undetectable		 2ab2A-3ounA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.96A 2eikC-3ounA:
undetectable
2eikJ-3ounA:
undetectable		 2eikC-3ounA:
19.85
2eikJ-3ounA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 8 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.89A 2eikP-3ounA:
undetectable
2eikW-3ounA:
undetectable		 2eikP-3ounA:
19.85
2eikW-3ounA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		3 / 3 LEU A  22
TYR A  32
GLN A  33
 None
 0.71A 2wekA-3ounA:
undetectable		 2wekA-3ounA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.90A 3ag2C-3ounA:
undetectable		 3ag2C-3ounA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.91A 3ag2P-3ounA:
undetectable
3ag2W-3ounA:
undetectable		 3ag2P-3ounA:
19.85
3ag2W-3ounA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.95A 3ag4P-3ounA:
undetectable
3ag4W-3ounA:
undetectable		 3ag4P-3ounA:
19.85
3ag4W-3ounA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.95A 3asnC-3ounA:
undetectable
3asnJ-3ounA:
undetectable		 3asnC-3ounA:
19.85
3asnJ-3ounA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  61
ILE A 106
GLU A  62
LEU A  75
SER A  38
 None
 1.49A 4r88A-3ounA:
undetectable		 4r88A-3ounA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  61
ILE A 106
GLU A  62
LEU A  75
SER A  38
 None
 1.47A 4r88B-3ounA:
undetectable		 4r88B-3ounA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  61
ILE A 106
GLU A  62
LEU A  75
SER A  38
 None
 1.47A 4r88C-3ounA:
undetectable		 4r88C-3ounA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  61
ILE A 106
GLU A  62
LEU A  75
SER A  38
 None
 1.50A 4r88D-3ounA:
undetectable		 4r88D-3ounA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  61
ILE A 106
GLU A  62
LEU A  75
SER A  38
 None
 1.49A 4r88E-3ounA:
undetectable		 4r88E-3ounA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  61
ILE A 106
GLU A  62
LEU A  75
SER A  38
 None
 1.50A 4r88F-3ounA:
undetectable		 4r88F-3ounA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.98A 5b1bP-3ounA:
undetectable
5b1bW-3ounA:
undetectable		 5b1bP-3ounA:
19.85
5b1bW-3ounA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.97A 5b3sC-3ounA:
undetectable
5b3sJ-3ounA:
undetectable		 5b3sC-3ounA:
19.85
5b3sJ-3ounA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  24
GLN A  23
PHE A  49
LEU A  51
 None
 0.99A 5b3sP-3ounA:
undetectable		 5b3sP-3ounA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3oun PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 6 ILE A  99
ALA A  86
THR A  82
VAL A  88
 None
 0.79A 5eclD-3ounA:
undetectable		 5eclD-3ounA:
12.80