SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ouo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		3 / 3 PHE A 149
LEU A 223
MET A 235
 None
 0.84A 1mx1D-3ouoA:
undetectable		 1mx1D-3ouoA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		5 / 12 SER A 105
THR A 115
SER A 148
ASN A  66
VAL A 179
 None
 1.21A 2nniA-3ouoA:
undetectable		 2nniA-3ouoA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 5 ALA A 139
PRO A 138
TYR A 140
ALA A 237
 None
 1.29A 3twpD-3ouoA:
undetectable		 3twpD-3ouoA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 7 VAL A 224
LEU A 223
MET A 152
VAL A 153
 None
 0.95A 4e1gB-3ouoA:
undetectable		 4e1gB-3ouoA:
15.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		6 / 11 GLY A  65
ASN A  66
LYS A  67
PRO A 127
PHE A 176
ILE A 180
 None
 1.03A 4j4vA-3ouoA:
33.3		 4j4vA-3ouoA:
38.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J4V_B_SVRB301_1
(NUCLEOCAPSID PROTEIN)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		5 / 10 GLY A  65
ASN A  66
LYS A  67
PRO A 127
PHE A 176
 None
 0.74A 4j4vB-3ouoA:
32.2		 4j4vB-3ouoA:
38.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		5 / 8 GLY A  65
ASN A  66
PRO A 127
PHE A 176
ILE A 180
 None
 0.88A 4j4vC-3ouoA:
20.1		 4j4vC-3ouoA:
38.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		5 / 11 GLY A  65
ASN A  66
PRO A 127
PHE A 176
ILE A 180
 None
 0.78A 4j4vD-3ouoA:
33.0
4j4vE-3ouoA:
32.6		 4j4vD-3ouoA:
38.71
4j4vE-3ouoA:
38.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		3 / 3 VAL A 204
SER A 170
MET A 145
 None
 0.89A 5ikqA-3ouoA:
undetectable		 5ikqA-3ouoA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3ouo NUCLEOPROTEIN
(Rift
Valley
fever
phlebovirus) 		4 / 5 PRO A 230
VAL A 234
GLY A 113
VAL A 153
 None
 0.99A 6ak3B-3ouoA:
undetectable		 6ak3B-3ouoA:
18.99