SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3our'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W13_A_ACTA1208_0 (ZINC METALLOPROTEINASE BAP1)	3our	PHOSPHOTRANSFERASE SYSTEM IIA COMPONENT (Vibrio vulnificus)	4 / 4	THR B 168 ARG B 166 GLU B 149 ASN B 151	None	1.03A	2w13A-3ourB: 0.0	2w13A-3ourB: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJT_D_017D101_2 (PROTEASE)	3our	PHOSPHOTRANSFERASE SYSTEM IIA COMPONENT (Vibrio vulnificus)	5 / 9	LEU B 27 GLY B 160 ASP B 118 VAL B 120 ILE B 23	None	1.16A	4njtD-3ourB: undetectable	4njtD-3ourB: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A5Z_C_WJZC304_0 (BETA-LACTAMASE NDM-1)	3our	PHOSPHOTRANSFERASE SYSTEM IIA COMPONENT (Vibrio vulnificus)	4 / 7	MET B 60 GLY B 101 ASN B 75 HIS B 76	None	1.29A	5a5zC-3ourB: undetectable	5a5zC-3ourB: 23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1805_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3our	PHOSPHOTRANSFERASE SYSTEM IIA COMPONENT (Vibrio vulnificus)	5 / 9	GLY B 29 LEU B 88 VAL B 139 ILE B 31 GLY B 155	None	1.00A	5vkqC-3ourB: undetectable 5vkqD-3ourB: undetectable	5vkqC-3ourB: 7.62 5vkqD-3ourB: 7.62

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2W13_A_ACTA1208_0","ZINC METALLOPROTEINASE BAP1","3our","PHOSPHOTRANSFERASE SYSTEM IIA COMPONENT","Vibrio vulnificus",4,"THR B 168;ARG B 166;GLU B 149;ASN B 151","None","1.03A","2w13A-3ourB:0.0","2w13A-3ourB:21.36"],["4NJT_D_017D101_2","PROTEASE","3our","PHOSPHOTRANSFERASE SYSTEM IIA COMPONENT","Vibrio vulnificus",5,"LEU B  27;GLY B 160;ASP B 118;VAL B 120;ILE B  23","None","1.16A","4njtD-3ourB:undetectable","4njtD-3ourB:19.59"],["5A5Z_C_WJZC304_0","BETA-LACTAMASE NDM-1","3our","PHOSPHOTRANSFERASE SYSTEM IIA COMPONENT","Vibrio vulnificus",4,"MET B  60;GLY B 101;ASN B  75;HIS B  76","None","1.29A","5a5zC-3ourB:undetectable","5a5zC-3ourB:23.67"],["5VKQ_C_PCFC1805_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3our","PHOSPHOTRANSFERASE SYSTEM IIA COMPONENT","Vibrio vulnificus",5,"GLY B  29;LEU B  88;VAL B 139;ILE B  31;GLY B 155","None","1.00A","5vkqC-3ourB:undetectable;5vkqD-3ourB:undetectable","5vkqC-3ourB:7.62;5vkqD-3ourB:7.62"]]