SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ouu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 LEU A 256
GLY A 226
VAL A 304
LEU A 330
LEU A 248
 None
 0.83A 1mx1D-3ouuA:
undetectable		 1mx1D-3ouuA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		4 / 5 SER A 301
VAL A 225
SER A 243
VAL A 300
 None
 1.28A 2j9cA-3ouuA:
undetectable
2j9cB-3ouuA:
undetectable
2j9cC-3ouuA:
undetectable		 2j9cA-3ouuA:
15.47
2j9cB-3ouuA:
15.47
2j9cC-3ouuA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 GLU A 318
ILE A 314
ILE A 104
LYS A  27
ILE A   6
 None
 1.30A 2j9dG-3ouuA:
1.1
2j9dH-3ouuA:
1.4
2j9dI-3ouuA:
1.5		 2j9dG-3ouuA:
15.47
2j9dH-3ouuA:
15.47
2j9dI-3ouuA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 LYS A  27
ILE A   6
GLU A 318
ILE A 314
ILE A 104
 None
 1.29A 2j9dG-3ouuA:
1.1
2j9dH-3ouuA:
1.4
2j9dI-3ouuA:
1.5		 2j9dG-3ouuA:
15.47
2j9dH-3ouuA:
15.47
2j9dI-3ouuA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 GLY A 105
PHE A 103
GLY A 273
ILE A  14
PHE A  92
 None
 1.48A 3ko0F-3ouuA:
undetectable
3ko0G-3ouuA:
undetectable		 3ko0F-3ouuA:
11.99
3ko0G-3ouuA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 ALA A  46
TYR A  42
ARG A  20
ALA A  15
 None
 1.02A 3twpA-3ouuA:
2.6		 3twpA-3ouuA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		3 / 3 TYR A 439
HIS A 443
ARG A 442
 None
 1.07A 4e7bC-3ouuA:
undetectable		 4e7bC-3ouuA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 TYR A 372
VAL A 377
ILE A 385
ILE A 411
 None
 0.88A 4lv9A-3ouuA:
undetectable		 4lv9A-3ouuA:
22.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		7 / 7 LYS A 238
ASN A 291
ARG A 293
GLN A 295
VAL A 296
GLU A 297
ARG A 338
 CA  A 459 ( 4.7A)
CA  A 458 (-4.3A)
None
None
None
None
None
 0.65A 4mv7A-3ouuA:
53.0		 4mv7A-3ouuA:
49.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 8 LEU A   7
ALA A  70
ILE A  50
SER A  60
ALA A  15
 None
 1.33A 4wboB-3ouuA:
undetectable		 4wboB-3ouuA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 ILE A 132
VAL A 279
ASP A 436
THR A 437
ASN A 438
 ANP  A 460 (-4.2A)
None
None
ANP  A 460 (-3.5A)
None
 1.06A 4xe0A-3ouuA:
undetectable		 4xe0A-3ouuA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		3 / 3 ARG A 363
VAL A 390
TRP A 391
 None
 1.19A 5fvoA-3ouuA:
undetectable		 5fvoA-3ouuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		3 / 3 ASP A  37
SER A  60
TYR A  61
 None
 0.90A 5glmA-3ouuA:
undetectable		 5glmA-3ouuA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		4 / 4 GLN A 213
VAL A 225
GLU A 302
ILE A 307
 None
 1.37A 5jncA-3ouuA:
undetectable		 5jncA-3ouuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		3 / 3 THR A 252
PRO A 244
ARG A 228
 None
 0.86A 5nd7B-3ouuA:
undetectable		 5nd7B-3ouuA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 PHE A  80
GLY A  82
ILE A  50
ARG A  11
ASP A  37
 None
 1.08A 6c2mC-3ouuA:
undetectable		 6c2mC-3ouuA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 LEU A  62
SER A  34
GLY A  53
ILE A  52
PHE A  85
 None
 1.09A 6ebpA-3ouuA:
undetectable		 6ebpA-3ouuA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 LEU A  62
SER A  34
GLY A  53
ILE A  52
PHE A  85
 None
 1.09A 6ebpB-3ouuA:
undetectable		 6ebpB-3ouuA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ouu BIOTIN CARBOXYLASE
(Campylobacter
jejuni) 		5 / 11 LEU A  62
SER A  34
GLY A  53
ILE A  52
PHE A  85
 None
 1.07A 6ebzC-3ouuA:
undetectable		 6ebzC-3ouuA:
11.34