SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ova'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 153
PHE A 154
LEU A   7
PHE A 238
THR A 188
 None
 1.43A 1a8uA-3ovaA:
undetectable		 1a8uA-3ovaA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 153
PHE A 154
LEU A   7
PHE A 238
THR A 188
 None
 1.43A 1a8uB-3ovaA:
undetectable		 1a8uB-3ovaA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 7 GLU A  41
LEU A  64
VAL A 111
LEU A  31
 None
EDO  A 701 (-3.7A)
None
None
 0.99A 1hk3A-3ovaA:
undetectable		 1hk3A-3ovaA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 7 GLY A 162
CYH A 242
PHE A 245
GLY A 159
 None
 0.71A 3ko0M-3ovaA:
undetectable
3ko0P-3ovaA:
undetectable		 3ko0M-3ovaA:
12.87
3ko0P-3ovaA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 5 LEU A 329
LEU A 400
GLY A 401
GLY A 405
 None
None
G  C   2 ( 3.4A)
None
 0.70A 3si7C-3ovaA:
undetectable
3si7D-3ovaA:
undetectable		 3si7C-3ovaA:
21.28
3si7D-3ovaA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 150
PHE A 154
PHE A 254
LEU A   7
 None
 1.01A 3wg7P-3ovaA:
undetectable
3wg7W-3ovaA:
undetectable		 3wg7P-3ovaA:
17.46
3wg7W-3ovaA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 155
GLU A 176
VAL A 226
ALA A 227
 None
 0.98A 4nkxA-3ovaA:
undetectable		 4nkxA-3ovaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 7 PHE A 421
LEU A 420
MET A 432
MET A 433
 None
 1.02A 4rjdB-3ovaA:
undetectable		 4rjdB-3ovaA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 8 TYR A 392
LEU A 308
ILE A 335
PHE A 279
 A  C  22 ( 4.5A)
None
None
None
 0.83A 4v04A-3ovaA:
undetectable		 4v04A-3ovaA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 7 LEU A 150
PHE A 154
PHE A 254
LEU A   7
 None
 0.97A 5b3sC-3ovaA:
undetectable
5b3sJ-3ovaA:
undetectable		 5b3sC-3ovaA:
17.46
5b3sJ-3ovaA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 7 LEU A 150
PHE A 154
PHE A 254
LEU A   7
 None
 0.95A 5b3sP-3ovaA:
undetectable		 5b3sP-3ovaA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ova CCA-ADDING ENZYME
(Archaeoglobus
fulgidus) 		4 / 5 LEU A 150
PHE A 154
PHE A 254
LEU A   7
 None
 1.05A 5x1bP-3ovaA:
undetectable		 5x1bP-3ovaA:
17.46