SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ovg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 12 HIS A 214
LEU A 184
HIS A  26
ASP A 272
ASP A 238
 ZN  A 363 (-3.5A)
None
ZN  A 362 (-3.5A)
ZN  A 362 (-2.7A)
None
 1.46A 1a4lB-3ovgA:
6.4		 1a4lB-3ovgA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 5 HIS A  24
HIS A 100
HIS A 186
HIS A 214
ASP A 272
 ZN  A 362 (-3.6A)
KCX  A 153 ( 4.1A)
ZN  A 363 (-3.5A)
ZN  A 363 (-3.5A)
ZN  A 362 (-2.7A)
 0.90A 1e9yB-3ovgA:
13.9		 1e9yB-3ovgA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		6 / 6 HIS A  24
HIS A  26
HIS A 100
HIS A 186
HIS A 214
ASP A 272
 ZN  A 362 (-3.6A)
ZN  A 362 (-3.5A)
KCX  A 153 ( 4.1A)
ZN  A 363 (-3.5A)
ZN  A 363 (-3.5A)
ZN  A 362 (-2.7A)
 0.93A 1fweC-3ovgA:
13.4		 1fweC-3ovgA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		3 / 3 ASP A 272
HIS A 214
HIS A  24
 ZN  A 362 (-2.7A)
ZN  A 363 (-3.5A)
ZN  A 362 (-3.6A)
 0.61A 1oe1A-3ovgA:
undetectable		 1oe1A-3ovgA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		3 / 3 ASP A 272
HIS A 214
HIS A  24
 ZN  A 362 (-2.7A)
ZN  A 363 (-3.5A)
ZN  A 362 (-3.6A)
 0.61A 1oe3A-3ovgA:
undetectable		 1oe3A-3ovgA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 6 LYS A 122
MET A 123
ALA A 126
GLU A 130
 None
 0.99A 1qhyA-3ovgA:
undetectable		 1qhyA-3ovgA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 12 ALA A 193
LYS A 221
ILE A 267
LEU A 258
ILE A 228
 None
 0.98A 1rb3B-3ovgA:
undetectable		 1rb3B-3ovgA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		3 / 3 LYS A  29
ASP A  22
CYH A 236
 ZN  A 362 ( 4.9A)
None
None
 1.27A 2br4F-3ovgA:
undetectable		 2br4F-3ovgA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 11 LEU A 258
TYR A 223
VAL A 233
GLY A 232
LEU A 235
 None
 1.41A 2bxeA-3ovgA:
undetectable		 2bxeA-3ovgA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 7 SER A 109
ASP A 106
ARG A 163
LEU A 164
 None
 1.11A 2cdqB-3ovgA:
undetectable		 2cdqB-3ovgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 8 LEU A 200
ARG A 174
SER A  96
VAL A 121
 None
None
KCX  A 153 ( 3.4A)
None
 1.21A 2qd2A-3ovgA:
undetectable		 2qd2A-3ovgA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		3 / 3 ASP A 272
HIS A 214
HIS A  24
 ZN  A 362 (-2.7A)
ZN  A 363 (-3.5A)
ZN  A 362 (-3.6A)
 0.63A 2xxgA-3ovgA:
undetectable		 2xxgA-3ovgA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		3 / 3 ASP A 272
HIS A 214
HIS A  24
 ZN  A 362 (-2.7A)
ZN  A 363 (-3.5A)
ZN  A 362 (-3.6A)
 0.63A 2xxgC-3ovgA:
undetectable		 2xxgC-3ovgA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 12 VAL A 185
SER A  96
VAL A 171
LEU A 112
LEU A 166
 None
KCX  A 153 ( 3.4A)
None
None
None
 1.31A 2zlcA-3ovgA:
undetectable		 2zlcA-3ovgA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 8 GLY A 139
ILE A 120
MET A 123
CYH A 124
 None
 0.55A 3ko0O-3ovgA:
undetectable
3ko0Q-3ovgA:
undetectable		 3ko0O-3ovgA:
16.57
3ko0Q-3ovgA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 8 ILE A  64
VAL A   9
THR A  79
ILE A  82
 None
 0.84A 3p4wC-3ovgA:
undetectable		 3p4wC-3ovgA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 5 HIS A  24
HIS A 100
HIS A 186
HIS A 214
ASP A 272
 ZN  A 362 (-3.6A)
KCX  A 153 ( 4.1A)
ZN  A 363 (-3.5A)
ZN  A 363 (-3.5A)
ZN  A 362 (-2.7A)
 0.90A 4h9mA-3ovgA:
4.8		 4h9mA-3ovgA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 7 VAL A  65
ILE A  64
LEU A 301
LEU A 296
 None
 0.80A 4l1wA-3ovgA:
8.3		 4l1wA-3ovgA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 12 GLY A  19
THR A  21
ILE A  64
THR A  66
GLY A  91
 None
 1.14A 4n48A-3ovgA:
undetectable		 4n48A-3ovgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 9 ALA A  83
GLY A  90
ILE A  57
ILE A  94
VAL A   9
 None
 1.09A 4nptA-3ovgA:
undetectable		 4nptA-3ovgA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		5 / 12 GLY A  11
ILE A  94
ASN A  92
GLY A 150
PHE A 328
 None
 1.14A 4obwA-3ovgA:
undetectable		 4obwA-3ovgA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		6 / 6 HIS A  24
HIS A  26
HIS A 100
HIS A 186
HIS A 214
ASP A 272
 ZN  A 362 (-3.6A)
ZN  A 362 (-3.5A)
KCX  A 153 ( 4.1A)
ZN  A 363 (-3.5A)
ZN  A 363 (-3.5A)
ZN  A 362 (-2.7A)
 0.85A 4ubpC-3ovgA:
2.9		 4ubpC-3ovgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 5 VAL A 243
TYR A 282
ILE A  50
THR A  66
 None
 1.34A 4ze1A-3ovgA:
undetectable		 4ze1A-3ovgA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		6 / 12 ALA A  85
ILE A  82
VAL A  93
GLY A  91
ILE A  57
ILE A  50
 None
 1.37A 5e5kA-3ovgA:
undetectable		 5e5kA-3ovgA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 5 HIS A 214
LEU A 169
TYR A 105
PHE A 104
 ZN  A 363 (-3.5A)
None
None
None
 1.47A 5igjA-3ovgA:
undetectable		 5igjA-3ovgA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 6 HIS A 186
HIS A  26
HIS A  24
HIS A 100
 ZN  A 363 (-3.5A)
ZN  A 362 (-3.5A)
ZN  A 362 (-3.6A)
KCX  A 153 ( 4.1A)
 0.89A 5ncdB-3ovgA:
4.3
5ncdC-3ovgA:
4.4		 5ncdB-3ovgA:
21.93
5ncdC-3ovgA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 6 HIS A  26
HIS A  24
HIS A 100
HIS A 186
 ZN  A 362 (-3.5A)
ZN  A 362 (-3.6A)
KCX  A 153 ( 4.1A)
ZN  A 363 (-3.5A)
 0.92A 5nelA-3ovgA:
4.7
5nelD-3ovgA:
undetectable		 5nelA-3ovgA:
21.93
5nelD-3ovgA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 7 ASP A 272
GLY A 274
ASP A 238
HIS A 186
 ZN  A 362 (-2.7A)
None
None
ZN  A 363 (-3.5A)
 1.07A 5nnwD-3ovgA:
undetectable		 5nnwD-3ovgA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 7 ASP A 272
GLY A 274
ASP A 238
HIS A 186
 ZN  A 362 (-2.7A)
None
None
ZN  A 363 (-3.5A)
 1.06A 5no9D-3ovgA:
undetectable		 5no9D-3ovgA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3ovg AMIDOHYDROLASE
(Mycoplasma
synoviae) 		4 / 5 ASN A 216
GLY A 155
HIS A 214
ASP A 272
 None
None
ZN  A 363 (-3.5A)
ZN  A 362 (-2.7A)
 1.28A 6gh9A-3ovgA:
undetectable		 6gh9A-3ovgA:
13.94