SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ovk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 3ovk AMINOPEPTIDASE P,
XAA-PRO DIPEPTIDASE
(Streptococcus
pyogenes) 		5 / 12 THR A  48
ILE A  47
VAL A  45
MET A  16
CYH A  12
 None
 1.32A 1wsvB-3ovkA:
undetectable		 1wsvB-3ovkA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ovk AMINOPEPTIDASE P,
XAA-PRO DIPEPTIDASE
(Streptococcus
pyogenes) 		4 / 6 LEU A  35
ILE A  47
ILE A 116
LEU A  80
 None
 0.97A 2xkwB-3ovkA:
undetectable		 2xkwB-3ovkA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3ovk AMINOPEPTIDASE P,
XAA-PRO DIPEPTIDASE
(Streptococcus
pyogenes) 		4 / 6 GLN A 110
TYR A 106
PHE A  97
LEU A 119
 None
 1.42A 3tgvB-3ovkA:
undetectable		 3tgvB-3ovkA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ovk AMINOPEPTIDASE P,
XAA-PRO DIPEPTIDASE
(Streptococcus
pyogenes) 		4 / 8 VAL A  83
LEU A  87
LEU A  21
GLY A  96
 None
 0.58A 5f1aA-3ovkA:
undetectable		 5f1aA-3ovkA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3ovk AMINOPEPTIDASE P,
XAA-PRO DIPEPTIDASE
(Streptococcus
pyogenes) 		5 / 11 ALA A  49
THR A  48
GLY A  20
ALA A  17
LEU A 128
 None
 1.10A 5lf7H-3ovkA:
undetectable
5lf7I-3ovkA:
undetectable		 5lf7H-3ovkA:
20.00
5lf7I-3ovkA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3ovk AMINOPEPTIDASE P,
XAA-PRO DIPEPTIDASE
(Streptococcus
pyogenes) 		5 / 11 ALA A  49
THR A  48
GLY A  20
ALA A  17
LEU A 128
 None
 1.09A 5lf7V-3ovkA:
undetectable
5lf7W-3ovkA:
undetectable		 5lf7V-3ovkA:
20.00
5lf7W-3ovkA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3ovk AMINOPEPTIDASE P,
XAA-PRO DIPEPTIDASE
(Streptococcus
pyogenes) 		3 / 3 PHE A   4
ARG A   8
GLN A   7
 None
 1.00A 6g1pB-3ovkA:
undetectable		 6g1pB-3ovkA:
16.18