SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3owq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A  95
VAL A 309
MET A 312
SER A 316
 None
 1.13A 1kb9A-3owqA:
undetectable
1kb9C-3owqA:
undetectable
1kb9D-3owqA:
undetectable
1kb9E-3owqA:
undetectable		 1kb9A-3owqA:
22.17
1kb9C-3owqA:
22.08
1kb9D-3owqA:
21.41
1kb9E-3owqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		3 / 3 ARG A 113
ARG A 205
ARG A  90
 None
 1.06A 1l7fA-3owqA:
undetectable		 1l7fA-3owqA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		3 / 3 ARG A 113
ARG A 205
ARG A  90
 None
 1.05A 1l7hA-3owqA:
undetectable		 1l7hA-3owqA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		4 / 7 ALA A 169
ASP A 168
GLY A 162
ILE A 158
 None
 0.86A 2fxdB-3owqA:
undetectable		 2fxdB-3owqA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		4 / 8 ALA A 169
ASP A 168
GLY A 162
ILE A 158
 None
 0.75A 3el9A-3owqA:
undetectable		 3el9A-3owqA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		5 / 10 THR A 139
SER A 141
SER A 137
GLY A 135
GLY A 134
 None
 1.32A 3ixlA-3owqA:
undetectable		 3ixlA-3owqA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		6 / 10 GLY A  79
ALA A  91
ASP A  92
ASN A 128
ILE A  95
VAL A 140
 None
 1.42A 3lzvA-3owqA:
undetectable		 3lzvA-3owqA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		5 / 12 ASN A 230
ASP A 210
ILE A 179
ASP A 178
ASP A 223
 None
 1.47A 3welA-3owqA:
undetectable		 3welA-3owqA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		4 / 6 ILE A  95
GLN A 221
ILE A 226
ASP A 223
 None
 1.20A 4w5qA-3owqA:
undetectable		 4w5qA-3owqA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		3 / 3 ASP A 219
GLY A 216
ASP A 210
 None
 0.67A 4xdtA-3owqA:
undetectable		 4xdtA-3owqA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		4 / 6 ILE A  95
GLN A 221
ILE A 226
ASP A 223
 None
 1.17A 4z4cA-3owqA:
undetectable		 4z4cA-3owqA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		4 / 6 ILE A  95
GLN A 221
ILE A 226
ASP A 223
 None
 1.22A 4z4dA-3owqA:
undetectable		 4z4dA-3owqA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		5 / 12 ALA A 169
ASP A 168
GLY A 162
ILE A 158
ILE A 244
 None
 1.08A 5t2zA-3owqA:
undetectable		 5t2zA-3owqA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 3owq LIN1025 PROTEIN
(Listeria
innocua) 		5 / 12 LEU A  77
ILE A 156
LEU A 166
GLY A 162
ASN A 159
 None
 0.94A 6qxsB-3owqA:
undetectable		 6qxsB-3owqA:
19.66