SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3owv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		4 / 8 ALA A 160
ASN A 182
LEU A 162
GLY A 168
 CL  A 401 ( 4.1A)
None
None
None
 0.84A 1rukH-3owvA:
undetectable
1rukL-3owvA:
undetectable		 1rukH-3owvA:
21.09
1rukL-3owvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		5 / 12 THR A 187
PRO A  49
VAL A 233
TYR A 265
VAL A 156
 None
 1.25A 1z9hA-3owvA:
undetectable		 1z9hA-3owvA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		5 / 12 THR A 187
PRO A  49
VAL A 233
TYR A 265
VAL A 156
 None
 1.24A 1z9hB-3owvA:
undetectable		 1z9hB-3owvA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		5 / 12 THR A 187
PRO A  49
VAL A 233
TYR A 265
VAL A 156
 None
 1.25A 1z9hC-3owvA:
undetectable		 1z9hC-3owvA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		5 / 12 THR A 187
PRO A  49
VAL A 233
TYR A 265
VAL A 156
 None
 1.23A 1z9hD-3owvA:
undetectable		 1z9hD-3owvA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		6 / 12 SER A 237
GLY A 163
ALA A 160
GLY A 159
THR A 121
LEU A 117
 None
CL  A 401 (-3.6A)
CL  A 401 ( 4.1A)
MG  A 300 ( 4.5A)
None
None
 1.45A 2nyuB-3owvA:
undetectable		 2nyuB-3owvA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		4 / 8 GLU A 240
LYS A  84
ASN A  81
ASN A  86
 None
 1.17A 3kp6A-3owvA:
undetectable
3kp6B-3owvA:
undetectable		 3kp6A-3owvA:
21.86
3kp6B-3owvA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		5 / 12 PHE A 173
ALA A  97
THR A 108
VAL A 109
LEU A 161
 None
 1.41A 4qzuA-3owvA:
undetectable		 4qzuA-3owvA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 3owv DNA-ENTRY NUCLEASE
(Streptococcus
pneumoniae) 		3 / 3 THR A  59
ASP A  60
ALA A  61
 None
 0.05A 5g5gB-3owvA:
undetectable		 5g5gB-3owvA:
23.65