SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ox4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 4 HIS A 101
LEU A 179
LEU A  19
LEU A  26
 None
 1.25A 1a4lD-3ox4A:
undetectable		 1a4lD-3ox4A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 277
HIS A 263
THR A 197
HIS A 198
 NAD  A1385 ( 3.6A)
FE2  A 501 (-3.3A)
None
FE2  A 501 (-3.3A)
 0.99A 1azmA-3ox4A:
undetectable		 1azmA-3ox4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 277
HIS A 263
THR A 197
HIS A 198
 NAD  A1385 ( 3.6A)
FE2  A 501 (-3.3A)
None
FE2  A 501 (-3.3A)
 0.89A 1bzmA-3ox4A:
undetectable		 1bzmA-3ox4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 5 THR A 197
ASP A 194
HIS A 277
HIS A 198
 None
FE2  A 501 (-2.2A)
NAD  A1385 ( 3.6A)
FE2  A 501 (-3.3A)
 1.19A 1ei6A-3ox4A:
undetectable		 1ei6A-3ox4A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 LEU A 187
THR A 139
LEU A 179
GLY A 182
 NAD  A1385 (-4.2A)
NAD  A1385 (-2.8A)
None
NAD  A1385 (-4.1A)
 0.90A 1gtiA-3ox4A:
undetectable		 1gtiA-3ox4A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 THR A 206
GLU A 201
ASP A 194
 None
None
FE2  A 501 (-2.2A)
 0.74A 1nt2A-3ox4A:
3.1		 1nt2A-3ox4A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_B_MTXB170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 10 ALA A  34
LEU A  26
LYS A  24
ILE A 136
LEU A  19
 None
 1.48A 1tdrB-3ox4A:
undetectable		 1tdrB-3ox4A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.12A 1v55C-3ox4A:
2.4
1v55N-3ox4A:
undetectable
1v55P-3ox4A:
2.4		 1v55C-3ox4A:
20.96
1v55N-3ox4A:
21.52
1v55P-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 11 ALA A 253
ALA A 140
GLY A 141
THR A 142
ALA A 143
 None
None
None
NAD  A1385 (-3.7A)
None
 0.91A 2f16H-3ox4A:
undetectable
2f16I-3ox4A:
undetectable		 2f16H-3ox4A:
20.25
2f16I-3ox4A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 11 ALA A 253
ALA A 140
GLY A 141
THR A 142
ALA A 143
 None
None
None
NAD  A1385 (-3.7A)
None
 0.91A 2f16V-3ox4A:
undetectable
2f16W-3ox4A:
undetectable		 2f16V-3ox4A:
20.25
2f16W-3ox4A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.12A 2y69C-3ox4A:
2.3
2y69N-3ox4A:
1.3
2y69P-3ox4A:
2.4		 2y69C-3ox4A:
20.96
2y69N-3ox4A:
21.52
2y69P-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.11A 3ablA-3ox4A:
1.5
3ablC-3ox4A:
2.4
3ablP-3ox4A:
2.4		 3ablA-3ox4A:
21.52
3ablC-3ox4A:
20.96
3ablP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.07A 3ablC-3ox4A:
2.3
3ablN-3ox4A:
undetectable
3ablP-3ox4A:
2.2		 3ablC-3ox4A:
20.96
3ablN-3ox4A:
21.52
3ablP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.16A 3abmA-3ox4A:
undetectable
3abmC-3ox4A:
2.4
3abmP-3ox4A:
2.3		 3abmA-3ox4A:
21.52
3abmC-3ox4A:
20.96
3abmP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.12A 3asnC-3ox4A:
2.4
3asnN-3ox4A:
1.0
3asnP-3ox4A:
2.4		 3asnC-3ox4A:
20.96
3asnN-3ox4A:
21.52
3asnP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.12A 3asoA-3ox4A:
0.9
3asoC-3ox4A:
2.4
3asoP-3ox4A:
2.3		 3asoA-3ox4A:
21.52
3asoC-3ox4A:
20.96
3asoP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.11A 3asoC-3ox4A:
2.3
3asoN-3ox4A:
undetectable
3asoP-3ox4A:
2.4		 3asoC-3ox4A:
20.96
3asoN-3ox4A:
21.52
3asoP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 11 ALA A 253
ALA A 140
GLY A 141
THR A 142
ALA A 143
 None
None
None
NAD  A1385 (-3.7A)
None
 0.88A 3mg0V-3ox4A:
undetectable
3mg0W-3ox4A:
undetectable		 3mg0V-3ox4A:
20.25
3mg0W-3ox4A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 12 LEU A 259
ASP A 194
HIS A 277
HIS A 263
ALA A 250
 None
FE2  A 501 (-2.2A)
NAD  A1385 ( 3.6A)
FE2  A 501 (-3.3A)
None
 1.34A 3r2jC-3ox4A:
3.8		 3r2jC-3ox4A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 12 LEU A 330
ALA A 224
LEU A 227
ALA A 195
ALA A 199
 None
 1.21A 3ut5D-3ox4A:
3.4		 3ut5D-3ox4A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 5 LEU A 380
PHE A 379
PRO A 351
ALA A 354
 None
 0.97A 3vm4A-3ox4A:
undetectable		 3vm4A-3ox4A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 277
HIS A 263
THR A 197
HIS A 198
 NAD  A1385 ( 3.6A)
FE2  A 501 (-3.3A)
None
FE2  A 501 (-3.3A)
 0.95A 3w6hA-3ox4A:
undetectable		 3w6hA-3ox4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.13A 3wg7C-3ox4A:
2.4
3wg7N-3ox4A:
undetectable
3wg7P-3ox4A:
2.2		 3wg7C-3ox4A:
20.96
3wg7N-3ox4A:
21.52
3wg7P-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.11A 3x2qC-3ox4A:
2.3
3x2qN-3ox4A:
1.8
3x2qP-3ox4A:
2.4		 3x2qC-3ox4A:
20.96
3x2qN-3ox4A:
21.52
3x2qP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 11 ALA A 216
ALA A 219
ALA A 220
VAL A 327
LEU A 285
 None
 1.03A 4j6cA-3ox4A:
undetectable		 4j6cA-3ox4A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 10 ALA A 216
ALA A 219
ALA A 220
VAL A 327
LEU A 285
 None
 1.03A 4j6cB-3ox4A:
undetectable		 4j6cB-3ox4A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 12 ALA A 216
ALA A 219
ALA A 220
VAL A 327
LEU A 285
 None
 1.02A 4j6dA-3ox4A:
undetectable		 4j6dA-3ox4A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 12 ALA A 216
ALA A 219
ALA A 220
VAL A 327
LEU A 285
 None
 1.02A 4j6dB-3ox4A:
undetectable		 4j6dB-3ox4A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 12 ALA A 216
ALA A 219
ALA A 220
VAL A 327
LEU A 285
 None
 1.03A 4jbtA-3ox4A:
undetectable		 4jbtA-3ox4A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 11 ALA A 216
ALA A 219
ALA A 220
VAL A 327
LEU A 285
 None
 1.02A 4jbtB-3ox4A:
undetectable		 4jbtB-3ox4A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 12 GLY A  17
ILE A 136
VAL A  11
VAL A  51
ILE A  93
 None
 0.81A 4q5mA-3ox4A:
undetectable		 4q5mA-3ox4A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.15A 5b1bA-3ox4A:
undetectable
5b1bC-3ox4A:
2.3
5b1bP-3ox4A:
2.3		 5b1bA-3ox4A:
21.52
5b1bC-3ox4A:
20.96
5b1bP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 12 GLY A 308
ALA A 224
ALA A 219
LEU A 217
ALA A 312
 None
 1.27A 5bw4B-3ox4A:
undetectable		 5bw4B-3ox4A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 6 PHE A 248
SER A 144
ALA A 143
HIS A 101
 None
NAD  A1385 ( 4.9A)
None
None
 1.19A 5dzkB-3ox4A:
undetectable
5dzkP-3ox4A:
undetectable		 5dzkB-3ox4A:
21.79
5dzkP-3ox4A:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 PHE A 248
SER A 144
ALA A 143
HIS A 101
 None
NAD  A1385 ( 4.9A)
None
None
 1.20A 5dzkd-3ox4A:
undetectable
5dzkr-3ox4A:
undetectable		 5dzkd-3ox4A:
21.79
5dzkr-3ox4A:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 PHE A 248
SER A 144
ALA A 143
HIS A 101
 None
NAD  A1385 ( 4.9A)
None
None
 1.20A 5dzkF-3ox4A:
undetectable
5dzkT-3ox4A:
undetectable		 5dzkF-3ox4A:
21.79
5dzkT-3ox4A:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 6 PHE A 248
SER A 144
ALA A 143
HIS A 101
 None
NAD  A1385 ( 4.9A)
None
None
 1.20A 5dzkg-3ox4A:
undetectable
5dzku-3ox4A:
undetectable		 5dzkg-3ox4A:
21.79
5dzku-3ox4A:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.10A 5iy5C-3ox4A:
2.3
5iy5N-3ox4A:
1.0
5iy5P-3ox4A:
2.4		 5iy5C-3ox4A:
20.71
5iy5N-3ox4A:
21.52
5iy5P-3ox4A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 11 THR A 188
ALA A 140
THR A 139
GLY A 182
LEU A  19
 None
None
NAD  A1385 (-2.8A)
NAD  A1385 (-4.1A)
None
 1.12A 5lf7H-3ox4A:
undetectable
5lf7I-3ox4A:
undetectable		 5lf7H-3ox4A:
20.47
5lf7I-3ox4A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 11 THR A 188
ALA A 140
THR A 139
GLY A 182
LEU A  19
 None
None
NAD  A1385 (-2.8A)
NAD  A1385 (-4.1A)
None
 1.10A 5lf7V-3ox4A:
undetectable
5lf7W-3ox4A:
undetectable		 5lf7V-3ox4A:
20.47
5lf7W-3ox4A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 198
ASP A 194
HIS A 277
 FE2  A 501 (-3.3A)
FE2  A 501 (-2.2A)
NAD  A1385 ( 3.6A)
 0.76A 5oexA-3ox4A:
undetectable		 5oexA-3ox4A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 277
ASP A 194
HIS A 198
 NAD  A1385 ( 3.6A)
FE2  A 501 (-2.2A)
FE2  A 501 (-3.3A)
 0.42A 5oexA-3ox4A:
undetectable		 5oexA-3ox4A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 198
ASP A 194
HIS A 277
 FE2  A 501 (-3.3A)
FE2  A 501 (-2.2A)
NAD  A1385 ( 3.6A)
 0.76A 5oexB-3ox4A:
undetectable		 5oexB-3ox4A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 277
ASP A 194
HIS A 198
 NAD  A1385 ( 3.6A)
FE2  A 501 (-2.2A)
FE2  A 501 (-3.3A)
 0.41A 5oexB-3ox4A:
undetectable		 5oexB-3ox4A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 198
ASP A 194
HIS A 277
 FE2  A 501 (-3.3A)
FE2  A 501 (-2.2A)
NAD  A1385 ( 3.6A)
 0.72A 5oexC-3ox4A:
undetectable		 5oexC-3ox4A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 277
ASP A 194
HIS A 198
 NAD  A1385 ( 3.6A)
FE2  A 501 (-2.2A)
FE2  A 501 (-3.3A)
 0.40A 5oexC-3ox4A:
undetectable		 5oexC-3ox4A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 198
ASP A 194
HIS A 277
 FE2  A 501 (-3.3A)
FE2  A 501 (-2.2A)
NAD  A1385 ( 3.6A)
 0.71A 5oexD-3ox4A:
undetectable		 5oexD-3ox4A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 277
ASP A 194
HIS A 198
 NAD  A1385 ( 3.6A)
FE2  A 501 (-2.2A)
FE2  A 501 (-3.3A)
 0.44A 5oexD-3ox4A:
undetectable		 5oexD-3ox4A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 6 ASN A 281
ALA A 282
PRO A 286
ASP A 194
 FE2  A 501 ( 4.3A)
None
None
FE2  A 501 (-2.2A)
 1.09A 5umd2-3ox4A:
undetectable
5umdF-3ox4A:
undetectable		 5umd2-3ox4A:
11.26
5umdF-3ox4A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.11A 5w97A-3ox4A:
undetectable
5w97C-3ox4A:
2.4
5w97c-3ox4A:
2.4		 5w97A-3ox4A:
21.52
5w97C-3ox4A:
20.96
5w97c-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.14A 5w97C-3ox4A:
2.4
5w97a-3ox4A:
undetectable
5w97c-3ox4A:
2.4		 5w97C-3ox4A:
20.96
5w97a-3ox4A:
21.52
5w97c-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 263
HIS A 277
HIS A 267
 FE2  A 501 (-3.3A)
NAD  A1385 ( 3.6A)
None
 0.73A 5waua-3ox4A:
undetectable		 5waua-3ox4A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.18A 5wauA-3ox4A:
1.4
5wauC-3ox4A:
2.4
5wauc-3ox4A:
2.4		 5wauA-3ox4A:
21.52
5wauC-3ox4A:
20.96
5wauc-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.16A 5wauC-3ox4A:
2.3
5waua-3ox4A:
1.4
5wauc-3ox4A:
2.3		 5wauC-3ox4A:
20.96
5waua-3ox4A:
21.52
5wauc-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.12A 5x19A-3ox4A:
undetectable
5x19C-3ox4A:
2.4
5x19P-3ox4A:
2.3		 5x19A-3ox4A:
21.52
5x19C-3ox4A:
20.96
5x19P-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.09A 5x1bA-3ox4A:
undetectable
5x1bC-3ox4A:
2.3
5x1bP-3ox4A:
2.4		 5x1bA-3ox4A:
21.52
5x1bC-3ox4A:
20.96
5x1bP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 263
HIS A 277
HIS A 267
 FE2  A 501 (-3.3A)
NAD  A1385 ( 3.6A)
None
 0.69A 5x1bN-3ox4A:
undetectable		 5x1bN-3ox4A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.07A 5x1fA-3ox4A:
undetectable
5x1fC-3ox4A:
2.4
5x1fP-3ox4A:
undetectable		 5x1fA-3ox4A:
21.52
5x1fC-3ox4A:
20.96
5x1fP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.15A 5xdqA-3ox4A:
1.1
5xdqC-3ox4A:
2.4
5xdqP-3ox4A:
2.4		 5xdqA-3ox4A:
21.52
5xdqC-3ox4A:
20.96
5xdqP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.10A 5xdqC-3ox4A:
2.3
5xdqN-3ox4A:
undetectable
5xdqP-3ox4A:
2.4		 5xdqC-3ox4A:
20.96
5xdqN-3ox4A:
21.52
5xdqP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.09A 5xdxC-3ox4A:
2.3
5xdxN-3ox4A:
undetectable
5xdxP-3ox4A:
2.4		 5xdxC-3ox4A:
20.71
5xdxN-3ox4A:
21.52
5xdxP-3ox4A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.17A 5z84A-3ox4A:
undetectable
5z84C-3ox4A:
2.2
5z84P-3ox4A:
2.4		 5z84A-3ox4A:
21.52
5z84C-3ox4A:
20.96
5z84P-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.13A 5z84C-3ox4A:
2.3
5z84N-3ox4A:
undetectable
5z84P-3ox4A:
2.3		 5z84C-3ox4A:
20.96
5z84N-3ox4A:
21.52
5z84P-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.14A 5z85C-3ox4A:
2.2
5z85N-3ox4A:
undetectable
5z85P-3ox4A:
2.4		 5z85C-3ox4A:
20.96
5z85N-3ox4A:
21.52
5z85P-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.11A 5z86C-3ox4A:
2.3
5z86N-3ox4A:
1.0
5z86P-3ox4A:
2.3		 5z86C-3ox4A:
20.96
5z86N-3ox4A:
21.52
5z86P-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.17A 5zcoA-3ox4A:
1.1
5zcoC-3ox4A:
2.2
5zcoP-3ox4A:
2.3		 5zcoA-3ox4A:
21.52
5zcoC-3ox4A:
20.96
5zcoP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.13A 5zcoC-3ox4A:
2.2
5zcoN-3ox4A:
undetectable
5zcoP-3ox4A:
2.4		 5zcoC-3ox4A:
20.96
5zcoN-3ox4A:
21.52
5zcoP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.16A 5zcpA-3ox4A:
undetectable
5zcpC-3ox4A:
2.4
5zcpP-3ox4A:
2.4		 5zcpA-3ox4A:
21.52
5zcpC-3ox4A:
20.96
5zcpP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.15A 5zcpC-3ox4A:
2.3
5zcpN-3ox4A:
1.1
5zcpP-3ox4A:
2.4		 5zcpC-3ox4A:
20.96
5zcpN-3ox4A:
21.52
5zcpP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.17A 5zcqA-3ox4A:
1.5
5zcqC-3ox4A:
2.4
5zcqP-3ox4A:
2.3		 5zcqA-3ox4A:
21.52
5zcqC-3ox4A:
20.96
5zcqP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 6 GLY A 344
ASP A 349
PRO A 276
GLY A 270
 None
 0.69A 6ag0C-3ox4A:
undetectable		 6ag0C-3ox4A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		3 / 3 HIS A 263
HIS A 277
HIS A 267
 FE2  A 501 (-3.3A)
NAD  A1385 ( 3.6A)
None
 0.73A 6giqa-3ox4A:
undetectable		 6giqa-3ox4A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 4 ALA A 199
ALA A 202
ALA A 216
ALA A 219
 None
 0.52A 6gtqA-3ox4A:
undetectable
6gtqB-3ox4A:
undetectable		 6gtqA-3ox4A:
17.66
6gtqB-3ox4A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 4 ALA A 216
ALA A 219
ALA A 199
ALA A 202
 None
 0.52A 6gtqA-3ox4A:
undetectable
6gtqB-3ox4A:
undetectable		 6gtqA-3ox4A:
17.66
6gtqB-3ox4A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 12 ALA A 253
ALA A 140
GLY A 141
THR A 142
ALA A 143
 None
None
None
NAD  A1385 (-3.7A)
None
 0.94A 6hwdH-3ox4A:
undetectable
6hwdI-3ox4A:
undetectable		 6hwdH-3ox4A:
12.01
6hwdI-3ox4A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		5 / 11 ALA A 253
ALA A 140
GLY A 141
THR A 142
ALA A 143
 None
None
None
NAD  A1385 (-3.7A)
None
 0.94A 6hwdV-3ox4A:
undetectable		 6hwdV-3ox4A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 8 LEU A 133
HIS A 198
THR A 147
HIS A 277
 None
FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
 1.09A 6nknC-3ox4A:
2.4
6nknN-3ox4A:
undetectable
6nknP-3ox4A:
2.4		 6nknC-3ox4A:
20.96
6nknN-3ox4A:
21.52
6nknP-3ox4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ox4 ALCOHOL
DEHYDROGENASE 2
(Zymomonas
mobilis) 		4 / 7 HIS A 198
THR A 147
HIS A 277
LEU A 133
 FE2  A 501 (-3.3A)
None
NAD  A1385 ( 3.6A)
None
 1.10A 6nmfA-3ox4A:
undetectable
6nmfC-3ox4A:
2.3
6nmfP-3ox4A:
2.4		 6nmfA-3ox4A:
21.52
6nmfC-3ox4A:
20.96
6nmfP-3ox4A:
20.96