SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oxk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN
(Entamoeba
histolytica) 		8 / 10 ILE A   6
PHE A   7
ILE A  10
ASP A  31
ILE A  32
LEU A  41
HIS A  99
HIS A 101
 None
5GP  A 125 (-4.9A)
None
5GP  A 125 (-2.6A)
5GP  A 125 (-3.7A)
5GP  A 125 (-4.7A)
5GP  A 125 (-3.9A)
5GP  A 125 (-4.1A)
 0.53A 3o1cA-3oxkA:
17.7		 3o1cA-3oxkA:
41.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN
(Entamoeba
histolytica) 		8 / 10 ILE A   6
PHE A   7
ILE A  10
ASP A  31
ILE A  32
LEU A  41
HIS A  99
HIS A 101
 None
5GP  A 125 (-4.9A)
None
5GP  A 125 (-2.6A)
5GP  A 125 (-3.7A)
5GP  A 125 (-4.7A)
5GP  A 125 (-3.9A)
5GP  A 125 (-4.1A)
 0.53A 3o1xA-3oxkA:
17.8		 3o1xA-3oxkA:
41.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN
(Entamoeba
histolytica) 		8 / 10 ILE A   6
PHE A   7
ILE A  10
ASP A  31
ILE A  32
LEU A  41
HIS A  99
HIS A 101
 None
5GP  A 125 (-4.9A)
None
5GP  A 125 (-2.6A)
5GP  A 125 (-3.7A)
5GP  A 125 (-4.7A)
5GP  A 125 (-3.9A)
5GP  A 125 (-4.1A)
 0.53A 3qgzA-3oxkA:
17.7		 3qgzA-3oxkA:
41.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN
(Entamoeba
histolytica) 		4 / 6 PHE A  29
ILE A  15
PRO A  16
PHE A  27
 5GP  A 125 (-4.6A)
None
None
None
 1.20A 4fgkA-3oxkA:
undetectable		 4fgkA-3oxkA:
19.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN
(Entamoeba
histolytica) 		5 / 8 ASN A  86
ALA A  91
GLN A  93
HIS A  99
HIS A 101
 5GP  A 125 (-3.7A)
None
None
5GP  A 125 (-3.9A)
5GP  A 125 (-4.1A)
 1.12A 5km8A-3oxkA:
15.2
5km8B-3oxkA:
18.2		 5km8A-3oxkA:
33.81
5km8B-3oxkA:
33.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN
(Entamoeba
histolytica) 		5 / 12 ILE A   6
ILE A  10
ASP A  31
LEU A  41
HIS A 101
 None
None
5GP  A 125 (-2.6A)
5GP  A 125 (-4.7A)
5GP  A 125 (-4.1A)
 0.51A 5km9B-3oxkA:
18.3		 5km9B-3oxkA:
33.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN
(Entamoeba
histolytica) 		7 / 12 PHE A   7
ILE A  10
ASP A  31
LEU A  41
VAL A  95
HIS A  99
HIS A 101
 5GP  A 125 (-4.9A)
None
5GP  A 125 (-2.6A)
5GP  A 125 (-4.7A)
None
5GP  A 125 (-3.9A)
5GP  A 125 (-4.1A)
 0.48A 5km9B-3oxkA:
18.3		 5km9B-3oxkA:
33.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN
(Entamoeba
histolytica) 		10 / 12 PHE A   7
ILE A  10
ASP A  31
ILE A  32
ASN A  33
LEU A  41
THR A  94
VAL A  95
HIS A  99
HIS A 101
 5GP  A 125 (-4.9A)
None
5GP  A 125 (-2.6A)
5GP  A 125 (-3.7A)
None
5GP  A 125 (-4.7A)
5GP  A 125 (-3.4A)
None
5GP  A 125 (-3.9A)
5GP  A 125 (-4.1A)
 0.49A 5uvmB-3oxkA:
18.0		 5uvmB-3oxkA:
40.54